Should a guy of AS genotype marry a lady with Genotype SC?

If you get married your chances of having a child who would have the genotype SS or SC are very high. While I would not discourage you(I know of a family of whom the mom and dad were AS and AS and had five AA or AS...and one SS with a high level of fetal hemoglobin....and I also know of another family with AS and AS who had six children...3 of whom were SS) I would advise you to think carefully of what you are about to undertake. If you really love each other....do consider not marrying as the costs of bringing up a very sick SS child would be too great.

One interesting fact....IVF may be able to help you and your intended to have healthy AS children...as the article quoted below explains.

[b]In vitro fertilization (IVF) combined with a procedure called Preimplantation Genetic Diagnosis (PGD) can improve a woman's chances of having a healthy baby when there is a family history of inherited genetic diseases or conditions, or if a patient has experienced miscarriages caused by embryo chromosomal abnormality.

Embryo biopsy with PGD is a procedure utilized in conjunction with IVF to screen for genetic and/or chromosomal problems before an embryo is selected for uterine implantation. This is also called "pre-pregnancy diagnosis". A number of genetic disorders and/or chromosomal abnormalities can be identified through PGD including Muscular Dystrophy, Hemophilia, Sickle Cell Anemia, Cystic Fibrosis, Tay Sachs, Fragile X Syndrome, Turner Syndrome, Huntington disease and Down syndrome.

"PGD allows us to differentiate abnormal embryos from the normal embryos, so that only normal embryos are transferred to the uterus," said Dr. Andrew Levi," a board certified reproductive endocrinologist and founder of Park Avenue Fertility and Reproductive Medicine in Trumbull, Connecticut. "In select patients, IVF with PGD can significantly decrease miscarriage rates and help women at risk for miscarriage achieve a successful pregnancy."

Dr. Levi reports that the majority of couples who proceed with IVF in conjunction with PGD either have experienced recurrent miscarriages; prior unexplained IVF failures; have conceived with a fetus or child with a chromosome abnormality; or have an identifiable or inheritable genetic medical conditions.

IVF entails stimulation of a woman's ovaries to obtain multiple eggs, subsequent removal of the eggs from the woman's body, fertilization of the eggs with the patient's partner's sperm, and transfer of the fertilized eggs (embryos) back to the woman's uterus. Embryo biopsy with PGD is performed typically three days after fertilization and before embryo transfer.[/b]

IVF is expensive...so discuss with a gynecologist about that option and how it could help with you having healthy AS children only.

Some more info....click here and here

Hi there, yeah you can but would you consider adoption? The chance of having an SS child is definitely there, if you can consider adoption then go right ahead, good luck

Thank to you Bushdoc..........but that IVF and PGD, can it b done in Nigeria?

tunjiiBEST: Thank to you Bushdoc..........but that IVF and PGD, can it b done in Nigeria?

IVF, yes...PGD...not so sure.

A gynecologist at your local teaching hospital or Federal Medical Center might be able to give you better information