Answer: Firstly, this is an obvious weakness. Weakness mean risk to an employer and they are looking for re-assurance that you will adapt to the new environment.

Relate your previous experience to similar situations where you moved departments and had a new role or were faced with new technology which you had to learn quickly. Turn this into a positive about "how you are able to adapt to changing circumstances and have a flexible approach. How you pick up new skills quickly. How you enjoy the challenge of the ever changing technology."

Try to broaden the answer by saying "we are all faced with a fast moving and changing environment which constantly presents new challenges. I have always been able to rise to these and perform effectively despite tight deadlines and little support."

Importantly, then go on to list examples of similar experiences where you have demonstrated such skills. This should close the issue in the interviewers mind and paint a positive picture.

Source: http://blog.cvwizards.com.ng/?p=320