Let us assume that, you want to setup all them pretty url stuffs like this.
Let us say the domain is like nairaland. And you know everyone has their profile.

So, if you visit nairaland.com/dhtml - > should load my profile. . .so stepwise, how will you
go about that on say an apache server, please be explicit. . .you can post codes if necessary.

1 rule to answering the question : - creating of folders for everybody is not acceptable.
1 hint to answering the question : - htaccess is allowed if necessary.

Mod_rewrite URL should solve that problem. I have used it in the past.

- nitation

Right on nitation. . .
The htaccess file looks somewhat like this

.htaccess

RewriteEngine On
RewriteCond %{REQUEST_URI} (.*) 
RewriteRule ^([_0-9a-z-]+)$ redirection.php?purl=$1 [L,QSA] 

As for the redirection.php, you will have to write that yourself. . .