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REFUTAL: Over Ripe Bananas Don't Have Tumor Necrosis Factor (TNF) - Nairaland / General - Nairaland

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REFUTAL: Over Ripe Bananas Don't Have Tumor Necrosis Factor (TNF) by bomsilaga(m): 11:05pm On Mar 16, 2016
I saw this post; https://www.nairaland.com/2991730/why-should-always-choose-bananas on Nairaland and decided to run it through for authenticity and wholla!! its FALSE

PROOF;
Critical review of these banana claims

We need to examine this pseudoscience even more carefully:

The “Japanese scientists” made no claim that there’s TNF in a banana, but the junk medicine pushers continue to make the claim, facts be damned. The problem is that anyone with a basic comprehension of biochemistry would understand that tumor necrosis factor (TNF) is a fairly complex protein, with a highly specific role in the human immune system (something notably lacking in a plant), so the chances that a banana would have some substance that exactly mimics or copies TNF is so tiny as to be close to impossible. A banana has no need for TNF, since it lacks an immune system of a vertebrate, so evolving a complex protein like TNF would be crazy; in fact, if it did, we’d have to rewrite our understanding of evolution. Let’s make this clear–we don’t have to rewrite evolution, because there is no TNF in bananas.
Even if we could assume that a banana makes TNF, the digestive tract would break down the complex proteins and substances, such as TNF, into its constituent components, such as amino acids, simple sugars, and fats, before being absorbed into the bloodstream. The TNF probably wouldn’t survive intact within the digestive tract. The true scientific skeptic would, even if they thought that maybe a banana evolved a TNF molecule by some strange mechanism, know that it could not enter the body. It is just not physiologically plausible.
But let’s pretend that TNF is produced in bananas (it doesn’t) and it can pass intact into the bloodstream from the digestive tract (it can’t), it would require eating hundreds of bananas to get a blood level of TNF that would actually have a biological effect. And even if TNF killed cancer cells (it doesn’t), how would your body “know” how to move the TNF to the cancer (it can’t). And which one of the 200 or so cancers would it effect? Moreover, the body would start down-regulating TNF in response to excess TNF in the blood, because TNF doesn’t do what you think it does.
The name, tumor necrosis factor, seems to imply that it kills cancers (it really doesn’t). I would have to write a 20 page paper just to describe how TNF is regulated and disregulated within the immune system both locally and generally in response to a wide variety of immune challenges, including cancers. It is incredibly complex, and the name is simply one given without consideration to future alternative medicine pushers who jump on it as the the “cure” to all cancers. It isn’t.
Of course, all of this leads us to what TNF actually does. It’s part of the inflammatory response, so TNF is associated with autoimmune disorders such as rheumatoid arthritis, ankylosing spondylitis, inflammatory bowel disease, psoriasis, hidradenitis suppurativa and refractory asthma.
And this “boost the immune system” myth? The immune system is an incredibly complex system, with an almost infinite number of interactions between various proteins, compounds, organs, factors, immunoglobulins, receptors and cells. As long as you’re healthy, so is your immune system, there is nothing you can do to make it stronger, better, or “boostier.” As I’ve said, vaccinations actually do boost the immune system, and they rely upon an appropriate immune response.
So here we go again. Someone reads that some scientists discovered bananas cure cancer. They didn’t dig up the actual paper to find out that the scientists didn’t actually say that it did. They didn’t think through the problem that bananas wouldn’t actually contain tumor necrosis factor or that the digestive tract wouldn’t actually absorb it. Or that you couldn’t possibly eat enough bananas to get enough TNF to do any good. Or that if you could that it would have some very bad effects.

LONG STORY SHORT
The bananas prevent cancer meme relies upon a misinterpretation of an unimportant “Japanese scientist study.”
The study was bad anyways.
There is no TNF in bananas.
Even if bananas had TNF, your digestive tract would destroy the TNF, breaking it into constituent molecules.
But even if it could pass through the digestive tract and enter the bloodstream, you couldn’t consume enough bananas to raise your blood level of TNF to actually have a biological effect.
And even you could raise your blood level of TNF, it’s name is a misnomer, since TNF doesn’t cause tumors to necrose. TNF, in fact, causes the inflammatory response, and numerous autoimmune disorders.
And if you downed that much TNF, you’d die. So sure, the cancer is dead. But so are you.
There are a few ways to actually prevent cancer, like not smoking. Consuming bananas is not one of those ways.
If you want to eat a banana, go ahead. It does have some benefits I’m sure. But rest assured that as much as you want to believe that bananas prevent cancer, the evidence does not support it. It’s not ever going to cure cancer. It’s not going to do make you live longer. It’s just going to provide nutrition.
http://www.skepticalraptor.com/skepticalraptorblog.php/ripe-bananas-prevent-cancer/

GO FOR FRESH YELLOW BANANAS

1 Like

Re: REFUTAL: Over Ripe Bananas Don't Have Tumor Necrosis Factor (TNF) by jmichlins(m): 11:14pm On Mar 16, 2016
I think i just told my family that false information because the mods could not verify the claims before pushing to fp is appaling. Please guys many people believe that whatever makes fp is true. The nigerian university lecturer claim and counter claim is still fresh in our minds so please take note

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