Misoprostol is a cytoprotective prostaglandin PGE1 analogue. It (PGE1) is an inexpensive, orally active, synthetic prostaglandin that is used for the prevention of gastric ulcers. It does not need refrigeration and has few gastrointestinal side-effects. Misoprostol has been used for medical abortion, cervical softening and induction of labor and treatment of postpartum hemorrhage.