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Third-hand smoke exposure can damage brain, liver, increase the risk of neurodegenerative diseases, and destroy metabolism. The research team analyzed how people were affected by inhaling smoke from smoker's clothes, hair, home, or car.

Being a third-hand smoker for one month can cause type 2 diabetes, hyperactivity, liver and lung damage, and wound-healing complications.
Exposure for two months resulted in further molecular damage, and at four to six months caused more damage, long-term exposure can leads to insulin resistance.

Researchers discovered that stress hormones, such as epinephrine, increased in one month of exposure.
Additional stress hormones are seen at two months, four months, and six months, eventually leading to immune fatigue.

Contaminants can be absorbed through the skin and through breathing. Exposure to tobacco smoke deposited on surfaces in homes and dust is a new form of toxicity. Noxious chemicals in tobacco smoke once deposited change in chemistry to become even more toxic and carcinogenic.
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