Smoking during pregnancy can be harmful for both mother and baby. Now, a new study provides further evidence that maternal smoking is a risk factor for cerebral palsy in offspring, and it has shed light on the mechanisms behind this association.
According to the Centers for Disease Control and Prevention (CDC), around 55 percent of mothers who smoke prior to becoming pregnant quit the habit during pregnancy.
However, around 10 percent of expectant mothers in the United States still smoke in the final 3 months of pregnancy.
Smoking during pregnancy is a risk factor for numerous health problems among offspring, including premature birth, birth defects - such as cleft lip, or cleft palate - and sudden infant death syndrome.
Previous research has also linked maternal smoking with a greater likelihood of cerebral palsy in children, but the processes underlying this association have been unclear.
The new study - led by Dr. Hui Chen, of the University of Technology Sydney in Australia - teaches us more about the subject.

Smoke exposure and cerebral palsy
Cerebral palsy is a movement and balance disorder that is estimated to affect around 1 in 323 children in the U.S.
The condition is caused by damage to the developing brain. This may occur before birth, during birth, within 1 month of birth, or in a child's early years.
One cause of cerebral palsy is the brain being starved of oxygen-rich blood in the womb, a process known as hypoxia-ischemic injury (HII).
The new research - recently published in the journal Frontiers in Molecular Neuroscience - reveals how exposure to cigarette smoke in the womb can worsen responses to HII, causing cell death in brain regions associated with motor skills and memory, which are regions implicated in cerebral palsy.
The researchers came to their findings by studying mice born to mothers that had been exposed to cigarette smoke before and during pregnancy.
The team tested the motor skills of the mouse pups and found that they demonstrated movement problems similar to those that arise in cerebral palsy.
"We found that pups from smoking mothers are more clumsy at adolescent age, have less strength in their limbs, are more anxious, and have poor memory function which many affect their learning ability," says Dr. Chen.

http://www.joeveng.com/2017/10/maternal-smoking-may-lead-to-cerebral.html

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