Monkeypox is a viral disease that produces pox lesions on the skin and is closely related to smallpox but is not nearly as deadly as smallpox was.

The history of monkeypox is not new (1958), and the first human cases were diagnosed and differentiated from smallpox in the early 1970s.Monkeypox virus causes monkeypox. The majority of cases are transmitted from animals (rodents) to humans by direct contact.

Person-to-person transfer, probably by droplets, can occur infrequently.Risk factors for monkeypox include close association with African animals (usually rodents) that have the disease or caring for a patient who has monkeypox.

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