From the humble surroundings of Huish Park to the glamorous stage of Wembley Stadium, Manchester United switch focus back to the Premier League for a crucial midweek clash against Tottenham Hotspur. The Reds make the trip to the capital looking to continue a 100 per cent winning run in 2018 (without conceding a goal) and extend the unbeaten run in the top flight to nine games. Victory would also move Jose Mourinho's men 11 points clear of fifth-placed Spurs in the table.
Both sides experienced contrasting fortunes when taking on League Two clubs away from home in the Emirates FA Cup fourth round at the weekend, with United easing past Yeovil Town with a 4-0 win on Friday night before Spurs drew 1-1 against lowly Newport County.
Alexis Sanchez could make his first Premier League appearance for United after a Man-of-the-Match display at Yeovil, while captain Michael Carrick could be in contention for a first league top-flight outing of the season (against his former club) after returning at Huish Park. Jose Mourinho told MUTV there are no new injuries to contend with and admitted he has a positive selection headache. He also gave an update on last season’s top scorer, Zlatan Ibrahimovic, who has been working on his match fitness.
For Spurs, it remains to be seen whether goalkeeper Hugo Lloris and Danish playmaker Christian Eriksen will be back, having missed the last two games, but injured trio Danny Rose, Serge Aurier and Harry Winks are expected to be sidelined again.
Tottenham have stuttered to successive 1-1 draws in their last two games against Newport and Southampton, following emphatic home wins over AFC Wimbledon and Everton. Mauricio Pochettino’s side are unbeaten in six league matches since a 4-1 defeat at leaders Manchester City in mid- December as they chase down Liverpool, who are two points ahead of them in fourth.
For the first time in history, United will play a Premier League game at Wembley Stadium - which is Tottenham's temporary home while a new ground is built at White Hart Lane. It's also our 50th match at the national stadium overall, with the record to date standing at 22 wins, 12 draws and 15 defeats – scoring 73 goals and conceding 55 in the process.


http://www.manutd.com/en/Fixtures-And-Results/Match-Reports/2018/Jan/Match-preview-Tottenham-Hotspur-v-Manchester-United-Premier-League-Wed-31-Jan-2018.aspx

MATCH FACTS
Head-to-head
Tottenham have lost 80 league matches to Manchester United, 11 more than against any other opponent.
United have only lost four of the last 33 top-flight meetings (W21, D8).
However, those four wins for Tottenham have come in the 11 most recent league encounters between the sides, including the last two at White Hart Lane.
Spurs last won three consecutive home league games against Manchester United between 1965 and 1966.

Tottenham Hotspur
Spurs have earned just three points in five games this season against Arsenal, Chelsea, Liverpool, Manchester City and Manchester United, which is fewer than any other current top-six side in these fixtures.
However, Tottenham have lost only one of their 31 league home fixtures since the beginning of last season.
They have gone 11 home matches without defeat in the league since losing to Chelsea in August, winning seven of their last nine games at Wembley.
Harry Kane has scored 99 goals in 139 Premier League appearances; only Alan Shearer (124) and Sergio Aguero (147) have reached a century of goals in fewer than 150 matches in the division.

Manchester United
United are unbeaten in eight league matches and have taken 16 points from their last six away games.
Jose Mourinho has won 12 matches against Spurs in all competitions, more than he has against any other opponent.
David de Gea has kept 14 clean sheets in the Premier League this season, the most by any goalkeeper in Europe's big five leagues.
Paul Pogba has not finished on the losing team in any of his last 36 Premier League appearances, dating back to October 2016.


http://www.bbc.co.uk/sport/football/42799044