Being that I have learned something about monetization at the website level and monetization in mobile applications, I dare to give you a concept, but hardly give you a figure, which will be clear shortly.

Let's suppose you have a video that goes viral on YouTube. That video is monetized with a strategy (there are several strategies and techniques, in addition to having several monetization points if the video has an appropriate length).

Can you calculate how much you are going to win beforehand ?

Hardly.

Let's see how Google would do to calculate how much you're going to win. This is a 'bird's eye algorithm' that simulates the calculation formula:

-What is the niche of this video?

- Is there a group of users that have an interest in this video? (either because it's a product, or a service)

- Are there companies or sponsors interested in this video that support the initiative, or have an interest in the users who watch this video?

This type of questions and dozens of other questions (which I ignore because only Google engineers know) are converted into algorithms that allow us to estimate how much to pay depending on the users who watch the video.

Example 1:

You make a compilation of bloopers that becomes highly viral with cats that wake up their owners. You do not promote any brand, you only monetize it and the content is yours and original (which is important, otherwise you'll be 'banned')
What is the niche? Bloopers-> This is a niche too vast and is not easily monetizable (you do not have a clear audience, you do not offer a service, nor a product, there are no sponsors interested in promoting bloopers).
The calculation algorithm makes the estimations: a default value that is usually very low in the order of 1 - 5 cents per thousand visitors.
In figures, you can have between 100 to 500 dollars for every million views of the video.
This can be interpreted as: 'another video from the heap that is not possible to create a defined audience to sell something'
The truth is that Google engineers already know in advance that the audience that has your video can not sell a product or offer something that becomes $$$. As a result, Google pays you as little as possible for the video, even if it's really viral and seen by millions of people.

On the other hand, what aspect can oscillate the monetary return between 100 and 500 dollars per million visits? Easy: the answer that your video has in front of the displayed ads. If your audience is interested in the products displayed and clicks on them, your return will increase, otherwise Google will pay as little as possible. Being that the audience is heterogeneous, and you can not sell any product, the clicks on the ads are scarce (usually in the order of 1 %% - 5 %% (1 to 5 per thousand ads displayed)). This whole process is a calculation in real time depending on the users who watch the video and the clicks made on the ads.

Example 2:

You are a camera enthusiast and make a comparison of 3 types of lens brands for a Nikon photographic equipment: Nikon 18-300, Tamron 18-300 and Tokina 18-300 lenses. You use a known actress to make the shots, you are original you create an attractive way to make the comparison and the video goes viral.
What is the niche? - First, look at this fact: the niche is clearly defined, the subject is closed and there is a product or service offered. Obviously, those who are dedicated to taking pictures with cameras will be interested, even the competition. On the other hand, you are encompassing the Nikon, Tamron and Tokina brands. The video will be formed by an audience fragmented by brand, but at the same time very defined: photographers and potential clients in the search for glasses. On the other hand, having involved a well-known actress, you are promoting the virality of other types of visitors, the followers of the actress, and maybe other types of visitors, that you will have to analyze in the analytics generated by Google for the video. The benefit is mutual: you advertise the actress and she brings you followers, which contributes to making the video viral. It is a round concept, where both parties benefit.
On the other hand, you have to have taken the job of adding an explanatory text to the video, where you especially detail the brands that make the analysis, the types of lenses and the actress that you use as a model. All this text gives a hint to Google that the video is going and what ads related to these brands can offer to the visitors while the video is displayed.
This text feeds the Google search engine so that photographers and followers do a search on Google and YouTube, which points them directly to the video, and they come pouring in to see it, going viral.
On the side of companies, there are lens suppliers and the brands themselves interested in spreading their products. This interest is translated into notices that the interested companies wish to display. Google orchestra based on the video and content that ads display that match the proposed video and user profile. If the visitor is a photographer, Google will try to display notices related to photographic products. How refined is this selection I do not know, but the more you know about the user's profile, the more likely Google will get a warning where the user has an interest and click on them.
If the visitor is a follower of the actress, notices related to the actress will be presented (remember that many actors and actresses promote brands of clothing, watches, perfumes, etc. etc. etc.) so the actress can generate so many benefits or more that photographic products if the ads are well coordinated with the user's profiles.
All very well up here, but how are we doing numbers? Well you've hit the nail on the head: your video is positioned in different niches, (from photography to aesthetic products, depending on the visitor), you have masses of visitors interested in the products and the niches in turn have companies that compete to position their products .
To top it off, the chances of the visitor clicking on the ads can be up to 10 times (to put a figure) higher (or more) than a viral video of a blooper. It is obvious: the visitor has a genuine interest in the video and related products.
As a result, the figures associated with visitors can be (and are) several higher orders, ranging from 1 to 50 or more dollars per thousand visitors. Of course, this figure will vary based on the responses of visitors to the ads and how successful Google has been in putting the right notice in front of the right audience.
Putting the right product in front of visitors requires effort, coordination and intelligence. Google for its part takes its good slice (as I understand, it is 50% of profits).

So it's possible that a video of bloopers goes viral, reaches 10 million visits and gives you (at best) $ 5,000 (or 2500, discounting Google's slice)

In comparison, a cleverly designed video, aimed at a consumer, and involving people who have followers can generate much more money with a tenth of the necessary public, because visitors are strongly interested in acquiring related products.

Because everything I tell here is calculated continuously and in real time, not even Google itself can predict how much you will win if a video goes viral. It depends on many factors, in addition to the response of the public to the campaigns.

Google can give you an estimate, but never an accurate value.

I hope you have been helpful!
source: QUORA

Summary please

Educative...