For more than 20 years, scientists at Scripps Research have chipped away at the challenges of designing an HIV vaccine.

New research which has been published in Immunity, shows that their experimental vaccine strategy works in non-human primates.

The new study shows that rhesus macaque monkeys can be prompted to produce neutralizing antibodies against one strain of HIV that resembles the resilient viral form that most commonly infects people, called a Tier 2 virus.

The research also provides the first-ever estimate of vaccine-induced neutralizing antibody levels needed to protect against HIV.
Source: Scripps Research Institute

To read more on the research, ��

https://thesciencecrews./2018/12/17/hiv-vaccine-protects-non-human-primates-from-infection/

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Viruses represent the greatest source of biological diversity on Earth. For small viruses such as human immunodeficiency virus (HIV), influenza virus, hepatitis B virus (HBV) and hepatitis C virus (HCV), sequencing of partial genomes has been widely used for research, but it also has important clinical applications.
One of the main reasons and applications to sequence viruses is the detection of drug resistance. For example, the management of highly active antiretroviral therapy (HAART) for HIV relies on viral sequencing for the detection of drug resistance variants. HAART has dramatically improved survival of patients with HIV, but successful therapy requires long-term suppression of viral replication with antiretroviral drugs, which may be prevented by impaired host immunity, sub-optimal drug penetration in certain tissue compartments and incomplete adherence of patients to therapy. When viral replication continues despite treatment the high mutation rate of HIV enables resistance variants to develop.
Sourse:https://www.cd-genomics.com/Viral-Genome-Sequencing.html