₦airaland Forum

kings20:
It's very very possible...A person that has AA means the S Gene was suppressed. It doesn't mean you the AA person no get the S Gene. That S hidden Gene can still pop out any time. That's why Two dark parents can give birth to a fair child or two short parents can still give birth to tall kids...

Go and goggle it
or meet your doctor for clarification

suppression in genotype, you just broaden my knowledge, send me your email address let me send you free copies of at least three major biochemistry textbooks free and some on genetics so that you wont be embarrassing yourself online

chieyine:
You think genetics is simple
Pls remind me your course of study?

When jambitos full here they make noise anyhow

i dont mean to disrespect your parents but they should be ashamed of you
A prospective 600lv medical students says genetics is hard for his or her understanding what a waste
My coruse of study? Thought you said am a jambite
Confused being! Dont go and be useful to yourself continue forming online medical doctor

Chidonc:
stop disgracing the medical profession and do more research on your own,
in genetics, if both her parents are AA they cant have an AS not even an AC child, someone is shouting de novo synthesis below. AA partner marrying an AC partner wont still give birth to AS, 75% probability for AA and 25% AC. AS and AC are two different genotypes, go back to your knowledge of biochemistry and argue with legniger, is either there was a mistake when her parents did their genotype testing, or the mother was having an affair better still the girl was looking for a way to end the relationship

We are talking about pathology here and you are mentioning Lehniger Biochemistry.

Ok oo

You want to remain dull, pls do

Tag me or not, this is the last time I will respond to you.

OPTIMUSPRIME08:
i dont mean to disrecpect your parents but they should be asahmed of you
A prospective 600lv mediacl students says genetics is hard for his or her understanding what a waste
My coruse of study? Thought you said am a jambite
Confused being! Dont go and be useful to your self continue froming online medical doctor

Disrespect
Ashamed
Course
Yourself
Forming

When you learn how to spell simple words, we can discuss.
Do well to bask in your foolishness and ignorance

See ya

Chidonc:
de novo synthesis has never has never been fingered to change mutation, do your research and comment back, Ac is a genotype on it own, probably a mistake during her parents testing, mixed results, her mum having an affair and she became the product or she was looking for a firm ground to end the relationship

Blood of Jeremiah

De novo synthesis in Biochemistry is different from De novo mutation in pathology

Instead of you to learn, you are just arguing

Illiteracy is really a Disease

Mammangaddafi:
Oga stop telling us your educational background and explain if you want to. I'm also a medical student. Saying this is possible is like saying parents with blood group A can give birth to a child with blood group O.

A medical student that doesn't know blood group A can give birth to O?
You are a compulsive liar.
You are not and can never be a medical student

Blood group A can either be AA or AO
When it is AO, and the second partner is also AO, why wont an OO child emerge.

Nairaland is a place where people claim who they are not

Biglittlelois:
Pls explain how AA and AA can give birth to AS.

Sweetheart, it is a phenomenon known as De novo mutation.
The child in this scenario will have some genetic or phenotypic makeup never found in the parents which might be alteration in the shape of the red cell both genetically and phenotypically.

It is rare but not impossible

A little googling about Denovo mutation will help solidify the knowledge

Chidonc:
AA AND AS CAN NEVER GIVE BIRTH TO SS, IT A ZERO POSSIBILITY.

You sound scared. Don't worry, it's rare

chieyine:
Blood of Jeremiah

De novo synthesis in Biochemistry is different from De novo mutation in pathology

Instead of you to learn, you are just arguing

Illiteracy is really a Disease

lol, pathologist sanu. calm down, if you want to discus genetics, biochemistry is the key, bot pathology, abeg you are the one disgracing yourself

Dudeweedlmao:
You sound scared. Don't worry, it's rare

prove it with articles and journal's, share us the links, we will read them, stop consoling yourself with it rear dont worry.

Chidonc:
lol, pathologist sanu. calm down, if you want to discus genetics, biochemistry is the key, bot pathology, abeg you are the one disgracing yourself

Hello Biochemist, this topic is far beyond u.
Maybe u can go and work in a brewery but for cases I have seen live, I will be in a better position to teach you.
A paternity test was done and confirmed that the father is the father of the child after the samples were sent abroad.

chieyine:
We are talking about pathology here and you are mentioning Lehniger Biochemistry.

Ok oo

You want to remain dull, pls do

Tag me or not, this is the last time I will respond to you.

look at these medicine miss road student,
pathology ke, what has pathology got to do with indept genetics, you can even argue with a zoologist on this one, we are not talking about studying of disease dear, it genetics we are discussing, if you must discuss genetics and mutation, it only biochemistry that can bail you out, stop trying to cover up.

chieyine:
Hello Biochemist, this topic is far beyond u.
Maybe u can go and work in a brewery but for cases I have seen live, I will be in a better position to teach you.
A paternity test was done and confirmed that the father is the father of the child after the samples were sent abroad.

name the hospital and I will send them a mail to validate your story, stop hiding face, you can also send me articles and journal's that validate your claim, I will apologize on front page, AA couples can never give birth to AS, and stop shouting mutation and denovo synthesis

Chidonc:
look at these medicine miss road student,
pathology ke, what has pathology got to do with indept genetics, you can even argue with a zoologist on this one, we are not talking about studying of disease dear, it genetics we are discussing, if you must discuss genetics and mutation, it only biochemistry that can bail you out, stop trying to cover up.

Pathology means deviations from the normal
When A parents give birth to SS or AS isnt it deviation from the normal
Mr Biochemist

Chidonc:
name the hospital and I will send them a mail to validate your story, stop hiding face, you can also send me articles and journal's that validate your claim, I will apologize on front page, AA couples can never give birth to AS, and stop shouting mutation and denovo synthesis

That is a link to research conducted
https://sicklecellanemianews.com/2018/04/03/genome-sequencing-some-symptoms-may-help-sickle-cell-diagnosis/?amp

chieyine:
Disrespect
Ashamed
Course
Yourself
Forming

When you learn how to spell simple words, we can discuss.
Do well to bask in your foolishness and ignorance

See ya

i guess you did not see the medical too illiterate

chieyine:
A medical student that doesn't know blood group A can give birth to O?
You are a compulsive liar.
You are not and can never be a medical student

Blood group A can either be AA or AO
When it is AO, and the second partner is also AO, why wont an OO child emerge.

Nairaland is a place where people claim who they are not

Dummy,and you think i was referring to the AO?. I don't have time to be arguing my status as a medical student with you just clarify us on the genotype Mr. Medical student.

Chidonc:
stop disgracing the medical profession and do more research on your own,
in genetics, if both her parents are AA they cant have an AS not even an AC child, someone is shouting de novo synthesis below. AA partner marrying an AC partner wont still give birth to AS, 75% probability for AA and 25% AC. AS and AC are two different genotypes, go back to your knowledge of biochemistry and argue with legniger, is either there was a mistake when her parents did their genotype testing, or the mother was having an affair better still the girl was looking for a way to end the relationship

I am so proud of you. You are knowledgeable. That lunatic is not a medical student.

Chidonc:
prove it with articles and journal's, share us the links, we will read them, stop consoling yourself with it rear dont worry.

It's rare, not rear dear. Stop hyperventilating.

chieyine:
Sweetheart, it is a phenomenon known as De novo mutation.
The child in this scenario will have some genetic or phenotypic makeup never found in the parents which might be alteration in the shape of the red cell both genetically and phenotypically.

It is rare but not impossible

A little googling about Denovo mutation will help solidify the knowledge

Hahaha...i have also read this from Google. We are talking about what is obtainable in reality not theorical stuff. I have read a lot of stuffs in Kumar, Davidson and other text that were in disparity with what i saw when i started my clinical rotations in medicine. You don't have to really on text and google to spew trash. Now tell me since it is possible for parents with AA genotype to give birth to a child with AS genotype, how many cases of such have you seen or how many have been reported world wide?

chieyine:
That is a link to research conducted
https://sicklecellanemianews.com/2018/04/03/genome-sequencing-some-symptoms-may-help-sickle-cell-diagnosis/?amp

you even sent a biochemistry material on gene sequencing to help identify genes to curb sickle cell anaemia, that article have nothing to do with our discussion, besides AC and AS are different not the same, make your research, A child suffering from CC has a higher life expectancy compared to an AS child take note.

Limitless72:
Well I wouldn't say it's absolutely impossible there's a very slim chance in genetics considering it could be caused by:

(a) genetic mutation i. e one way or the other the DNA( deoxyribonucleiacid) of the organism that contains the genetic information has been ultered either by microorganisms/parasite ( bacteria, virus, fungi), by drugs,or complications during pregnancy, exposure to other biotic and abiotic factors.

(b) recessive gene: Probably the one of the parent(s) father, mother, grandfather or grandmother had an AS gene...ND it's was probably suppressed by the dominant gene of either parent(s)...

(c) one of either parent had extra marital coitus....

PS: What's written above is my two cent.. There's every possibility that I'm completely wrong.. No insult pls, if you feel my conjecture is false, you should but forward a superior hypothesis that invalidate mine...
I did human embryology, bacteriology,genetics, organic chemistry et al as borrowed courses in the university that year....So I still have little idea...Lolz

The case of co-dominance is only obtainable in blood group where all the genes are dominant and can all be express. You can't use the same theory when it pertains to the genotype.

Dudeweedlmao:
It's rare, not rear dear. Stop hyperventilating.

thanks bro, no one is above typo errors, but it doesn't change the argument here.

Mammangaddafi:
The case of co-dominance is only obtainable in blood group where all the genes are dominant and can all be express. You can't use the same theory when it pertains to the genotype.

sir I think we are wasting our time here arguing with possible prescience students, am sure the one claiming 600l medical student cant withstand a good ss3 pupil with good knowledge of secondary school biology.

Chidonc:
sir I think we are wasting our time here arguing with possible prescience students, am sure the one claiming 600l medical student cant withstand a good ss3 pupil with good knowledge of secondary school biology.

Exactly...

Mammangaddafi:
Dummy,and you think i was referring to the AO?. I don't have time to be arguing my status as a medical student with you just clarify us on the genotype Mr. Medical student.

You said this

Mammangaddafi:
Oga stop telling us your educational background and explain if you want to. I'm also a medical student. Saying this is possible is like saying parents with blood group A can give birth to a child with blood group O.

And I replied with this

chieyine:
A medical student that doesn't know blood group A can give birth to O?
You are a compulsive liar.
You are not and can never be a medical student

Blood group A can either be AA or AO
When it is AO, and the second partner is also AO, why wont an OO child emerge.

Nairaland is a place where people claim who they are not

You called me a dummy maybe the world should tell us who the dummy is between the two of us

Chidonc:
you even sent a biochemistry material on gene sequencing to help identify genes to curb sickle cell anaemia, that article have nothing to do with our discussion, besides AC and AS are different not the same, make your research, A child suffering from CC has a higher life expectancy compared to an AS child take note.

You didnt see the research about De Novo mutation.
I rest my case
See ya

Mammangaddafi:
Hahaha...i have also read this from Google. We are talking about what is obtainable in reality not theorical stuff. I have read a lot of stuffs in Kumar, Davidson and other text that were in disparity with what i saw when i started my clinical rotations in medicine. You don't have to really on text and google to spew trash. Now tell me since it is possible for parents with AA genotype to give birth to a child with AS genotype, how many cases of such have you seen or how many have been reported world wide?

Kumar and Clark, Davidson.
Can u pls reproduce that de novo mutation cant lead to sickle cell anaemia.

I have seen a case in UNTH.
The father is AA and the mother AS and they gave birth to SS.
He was told to do paternity test.
He returned back with the claim that the child is his.

You havent seen a case before doesnt mean that they don't exist.

You want to know if I am a medical student as claimed?
Ask for the Speaker, Faculty of Medical Sciences University of Nigeria

If you dey Idi Araba, I go soon come Lagos for a research program sponsored by Nigeria Institute of Medical Research

chieyine:
You didnt see the research about De Novo mutation.
I rest my case
See ya

lol, you where shouting de novo biosynthesis in pathology before not biochemistry na, stop fooling yourself na, I thought you said your own de novo biosynthesis is in pathology

chieyine:
Blood of Jeremiah

De novo synthesis in Biochemistry is different from De novo mutation in pathology

Instead of you to learn, you are just arguing

Illiteracy is really a Disease

have you forgotten this your reply on de novo biosynthesis, why sending me biochemistry articles.

Chidonc:
sir I think we are wasting our time here arguing with possible prescience students, am sure the one claiming 600l medical student cant withstand a good ss3 pupil with good knowledge of secondary school biology.

As old as u are, I can bet that You can't even get admission into my Secondary school now self

Chidonc:
have you forgotten this your reply on de novo biosynthesis, why sending me biochemistry articles.

I said De novo mutation not De Novo biosynthesis or anything of sort