20-year-old BrookeBrooke Greenberg may be 20
years old, but she remains forever trapped inside
the body and mind of a toddler , due to a
mystery medical condition that has baffled
medical experts for years.
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"From age one to four, Brooke changed. She got
a little bit bigger," explained her father, Howard,
during the family's appearance on Thursday's
"Katie" with Katie Couric. "But age four, four to
five, she stopped."
Since then, Brooke's height and weight of 16
pounds and 20 inches have remained a constant.
She wears diapers, is pushed in a stroller, gets
fed through a feeding tube due to a too-small
esophagus, and communicates like an infant
would, estimates her mother Melanie.
"Like 6 months," she explained on the show. "If
she's happy, she'll giggle and laugh."
Doctors have told Melanie and Howard, who live
in Maryland, that there is no other known case
like Brooke's in the world. And at least one
medical expert believes that Brooke's condition
could hold the key to the fountain of youth.
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"Here's a woman 20 years old who has literally
stopped aging," explained Dr. Eric Schadt,
director of the Icahn Institute for Genomics and
Multi-Scale Biology at Mt. Sinai Medical Center in
New York, who also appeared on the broadcast.
He said he took an interest in Brooke's case after
years of her receiving no diagnosis from other
doctors, and that her case could "blow a whole
field of science wide open."
In the meantime, the parents provide care to her
day in and day out, and have watched their
younger daughter, 17-year-old Carly, eclipse her
older sister by developing normally over the
years. They admit they have often felt isolated in
their struggle.
"It hasn't been easy," Melanie told Couric. "We
don't have anybody really to turn to, to tell us
what to expect." Doctors have no way to even
determine how long Brooke may live.
Still, her parents say they take solace in the fact
that she's here now, and believe she does not
need to be cured of anything.
"If somebody knocked on the door right now and
said, 'It's a guaranteed pill. Give this to Brooke
and she'll be fixed,' well first I would say to him,
'She's not broken.' And B, I would say, 'Thank
you, but no thank you," Howard said in a video
filmed for the "Katie" show.
To research Brooke's condition, scientists are
reading every single letter of the young woman's
DNA. "That would fill, like, 3,000 of the Harry
Potter books that my kids like. That's how big her
genome is," Dr. Schadt explained, adding that,
so far, scientists have put her genes in fruit flies
to see if it helps them live longer. He added that
the Greenberg's take solace in the fact Brooke
has also helped with research into conditions
including Alzheimer's, heart disease and cancer.
"That," he said, "is a pretty amazing gift to be
able to give to humanity."

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