I think what I have below are the most difficult course to
study in any Nigerian universities.

1) Medicine & surgery: In the field of medicine, it is another
world of studies because you will find yourself studying for
many years, some may succeed but some will deviate to
another major.

2)Law: being a law student is what most of aspirants wants
but law is just like medicine you will spend most of your
time in school also spending your time reading many books

3)Engineering: the field of engineering is the field of
technology, not only being a technician, you must also apply
the knowledge of mathematics to your work. that is, it
entails lots of calculation. it is said that there is no fine boy
in engineering department because all don't have time for
that.

4)Mathematics: we all know what mathematics is all about
and what it takes, a mathematician is a professional in
mathematics, mathematics. involves lots of calculation
thought your life.

5)Statistics:this is another discipline that is just like
mathematics, statisticians are applied mathematicians, they
use mathematics to solve real life problems, it entails lots of
mathematics and some borrowed courses that are not even
part of your discipline (eg, economics)

6)Chemistry: you guys may be surprise about this major but
chemistry is not an easy course, chemistry is really a broad
course, you find out using your time mixing chemicals in the
lab and cramming formulars and theories.

7) Architecture: Archi is another discipline that in which you
spend most of your time in school, at times you sleep in
school drawing and sketching diagrams for planning.
cc : lalasticlala, Ishilove.

No course is difficult to study

Your brain is just dry that's all....there is no difficult course

Research about vetinary medicine,it should be no.1 it involves various animals unlike medicine which is about only humans . . And also Dentistry and dental surgery should be no.2,that course is harder than medicine too(if you doubt me,ask any medicine student which has faculty of dentistry in his/her school) ,they write 2 m.b.b.s while medicine write 1.