Triclosan used in soap and Colgate toothpaste may increase the risk of bowel cancer, trials on mice revealed it may lead to inflammatory bowel disease IBD by changing their gut microbiota. According to University of Massachusetts Amherst researchers, triclosan triggered inflammation in the colons of mice.

Animal studies have shown triclosan can potentially change hormone systems in men and women and led to miscarriages in female rats, other trials have linked it to causing antibiotic resistance.

Mice were exposed to low amounts of triclosan for a short period of time before they were analysed by researchers. Scans revealed the ingredient caused them low-grade colonic inflammation and worsened colitis – one form of IBD. Further inspections showed it also exaggerated colitis-associated colon cancer.
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