The Director General of the National Agency for Food and Drug Administration and Control, Prof Mojisola Adeyeye, on Monday, ordered manufacturing of chloroquine for emergency stock for possible clinical trial treatment of coronavirus.

The NAFDAC boss in a statement, said the anti-malaria drug was reported to function as anti-viral at both the entry and post-entry stages of 2019-nCoV infection. She added that chloroquine had also been reported as potential broad spectrum anti-viral drug.

She noted that Lagos would begin clinical trial of the drug to evaluate its effectiveness , while calling on the public to desist from its use without the guidance of a medical doctor or clinician for cases of clinical trial treatment of COVID-19.

She said, “Chloroquine, an old anti-malarial, is being re-purposed for the clinical trial treatment of coronavirus 2019-nCoV. The drug was first tested in vitro (in the lab) using standard assays to measure the effects on the cytotoxicity, virus yield and infection rates of 2019-nCoV.

“The drug was reported to function as antiviral at both the entry and post-entry stages of 2019-nCoV infection . Chloroquine has also recently been reported as potential broad spectrum antiviral drug. In a very recent publication, chloroquine was reported in a press briefing by the State Council of China, indicating that chloroquine phosphate had demonstrated marked efficacy and acceptable safety in treating COVID-19 associated pneumonia in a multi-center clinical trial conducted in China.

“The study involved 10 hospitals in Wuhan, Jingzhou, Guangzhou, Beijing, Shanghai, Chongqing and Ningbo, and 100 patients. The investigators reported that chloroquine phosphate is superior to the control in inhibiting the pneumonia associated with COVID-19, and shortening the course of the disease.”

The DG of NAFDAC noted that the drug was discontinued in Nigeria many years ago for use as anti-malarial because of the resistance that the parasite developed against it.

She said, “Therefore, sourcing the raw material – active pharmaceutical ingredient- chloroquine phosphate could be difficult.

“About four weeks ago, I approached a local manufacturing company (May and Baker), a member of Pharmaceutical Manufacturing Group of Manufacturing Association of Nigeria, whose flagship product in the past was chloroquine, to make a batch of the drug for emergency stock. The company had NAFDAC approval for the production of the drug as anti-malarial many years ago before the discontinuation.”

According to Adeyeye, despite initial difficulty expressed by the managing director of the company, the hurdle was later removed, leading to the production of the drug with more to be manufactured.

She added, “He called shortly after that he was able to get the API and was asked to manufacture a batch for emergency stock just in case more people become exposed and infected with the virus. The batch has been manufactured and the company plans to make more batches if needed.

https://www.google.com/amp/s/punchng.com/nafdac-orders-emergency-chloroquine-production/%3famp=1

The same chloroquine?

By 10am ds morning,, God would reveal himself to mankind.. Today corona will be thing of d past says the Lord,, God of all flesh...

Don't bother to quote me, am just his messenger... But believe!!!

Am glad a lot of people are awake,, corona is a loser,, thou says the LORD of host.. He will not fold his hands and allows what he wonderfully made to be destroyed by men of the world..

Lets all join our heart in prayers..

Hmmmmmmm!

Till now?

The Director General of the National Agency for Food and Drug Administration and Control, Prof Mojisola Adeyeye, on Monday, ordered manufacturing of chloroquine for emergency stock for possible clinical trial treatment of coronavirus.

The end of Covid-19 is upon us. Halleluyah

nobone:
The same chloroquine?

Yes, Same one

Overdose loading

edo3:
By 10am ds morning,, God would reveal himself to mankind.. Today corona will be thing of d past says the Lord,, God of all flesh...

Don't bother to quote me, am just his messenger... But believe!!!

I say Amen

The good news is that we still have chloroquine around even with the said discontinuation of its production. Let Nafdac give more companies the right to produce the drug.

Follow follow country..

.

Good news

I hope it has been refined

I believe Nigeria will disappoint the whole world.

Thank God, we will pass over this

edo3:
By 10am ds morning,, God would reveal himself to mankind.. Today corona will be thing of d past says the Lord,, God of all flesh...

Don't bother to quote me, am just his messenger... But believe!!!

Amen. I believe

Thank God o.

But just imagine 1 small sickness that ordinary chloroquine can cure shut down the whole world. Knowledge is power indeed.

That's how it will be the day they will discover a cure to HIV

The stone which the builders refused has become the head stone of the corner.

Every condemnations from our enemies will work in our favour in Jesus name..AMEN.

What I have noticed about this coronavirus is that if you have 5 symptoms and have different drugs that can combat those 5 different illnesses then you should be fine. This virus will not come near us and will end soon by God's grace. Also adhere to all precautionary measures rolled out by NCDC and WHO. Stay safe my people.

Nice update

Naija

Why did it take them so long to order clinical trials

nwanna89:
Same chloroquine that was banned by same nafdac.

In as much as this development is welcome, has the root cause of its initial ban been addressed?

It was banned because the malaria parasite had grown resistant to it, continuing it's production wasn't advised.

Thank God o. I'm tired of staying at home

Hmmm

We shall survive dis

Soon any drug wey get quine for him name wont be available.

That chloroquine dey itch body die, i so dislike it