Luu40:


Evolution, in my understanding is very true to a large extent. But there are certain things I totally disagree with - one of which is the various theories of creation.

just2endowed:
o

well humans mutate overtime on the long run.

here in west africa, we have mosquitoes dealing withhumans. as time goes on, the human body try to develop antidots for these killer disease and because we continue to mutate to beat this malaria, the blood turns sickle, thats how we came about these genotype.

U will be suprised that in europe and up north pole, they are almost all AA not until blacks migrate to the west and up north that small percentage came out AS.

so, in all, the culprit of all these is one animal. Mosquitoes

maisauki:

I'm a descendant of Adam nitemi, not from one ape

Rumundele:
Bros no genotype is AC otherwise i fit tell you my own genotype is AK. Don't mind me sha, AC is rare and both AS and AC are abnormal

OCHKESTINE:
My mum and Dad are both AS, they gave birth to 10 kids,
only me came out AA,
9 SS, we lost 6.

So I carry the burden of taking care of the 3 alive and my aged parents.

This year alone 2 have received blood transfusion with both PCVs dropping below 15% (This happens regularly).

Due to their crisis, I have black market pharmacies where they trust me to sell me Tramadol/Tramol because mere Painkillers don't work for them.

I am not the first child but life has automatically put me first since I am better health-wise.

I love my family and there is no length I won't go for them.

When I was to get married, I made sure my wife was AA, In fact, because of my sick siblings, I don't like slim ladies

Blake755:
Too sad but it still worth it
But i need answers oo if it's God who created first man and woman then how did ss genotype come into existence

seunH:
Actually sir, originally, all genotypes were AA. But as a result of mutation which was passed on to offspring, one of the A in the AA changed to S hence we now had the AS genotype. Interestingly AS confers resistance to malaria especially in Sub Saharan Africa. That's why the genotype seems to thrive over here.

MrB0LD:


I have seen AS that comes down with malaria almost every month. When he wakes up, he'll be like, "I have been bitten by mosquitoes..."
Cos his body temperature will just skyrocket.

While his younger brother is AA, but that one hardly falls sick in a year. Even if he does, only on rare occasions he takes drugs.
How do u explain this?

TechnologyGuru:

I gave an explanation for the origination of the S-gene in AS genotype.
The last two statements in my explanation are just basic assumption.. Definitely doesn't hold in all cases.

MrB0LD:


I have seen AS that comes down with malaria almost every month. When he wakes up, he'll be like, "I have been bitten by mosquitoes..."
Cos his body temperature will just skyrocket.

While his younger brother is AA, but that one hardly falls sick in a year. Even if he does, only on rare occasions he takes drugs.
How do u explain this?

Jeon:


Before excuses was Money, no wife material, no love, and now genotype wants to take the lead.

Very funny.

nairalanda1:


There is AC genotype...which if two of them marry, they have a child with a variant of RED BLOOD cell called due to HbSC.

Infact the 4 types of genotypes are

AA, AS, AC, and SS.

A child with hemoglobin C has a mild anemia basically.

DO YOU NEED TO KNOW MORE?

Bigchristo:
I swear he is a lucky guy, I heard they later have another child because the prediction was that after 1-3 kids the next maybe SS we’ve lost contact since about 4yrs that I traveled out of the country and he also travel too, I pray for him not to have any SS kids because my neighbor back then I see the shege they went through

Luu40:


Kindly check this link https://www.hopkinsmedicine.org/health/conditions-and-diseases/sickle-cell-disease#:~:text=Sickle%20cell%20is%20an%20inherited,%22carrier%22%20of%20the%20disease.

Is there anything you could help me with to undunce my writing? I'm a chemist by university degree and a self-taught data analyst.

micxwell:
No o! This is wrong bro. The correct interpretation should be that the parents have a 25% chance of giving birth to an SS child per pregnancy. Hence, the same chance still applies to the fourth baby.

micxwell:
You interpreted the family history wrongly though. Even if people had died in any of both families as a result of Sickle Cell diseases, marrying someone who is not a carrier will definitely cancel it all out. That family you mentioned up there are just plain ignorant and prolly stubborn🤷

Luu40:


Family history wrongly? Please elaborate

micxwell:

The information your write-up passed across especially where you mentioned your mum was that, since people had died as a result of Sickle Cell Disease in your in-laws family; their genes are responsible for your nephew/niece's predicament. It's actually not so. Whether the family has had cases of death due to Sickle Cell or not; if two couples with matching AS genotypes come together the chance remains.

Rumundele:

You are a bad guy, you are a very bad guy. Hope you get it, if you don't get it forget about it.

heykims:

Just pray u don't birth an SS because that might be the beginning of the nightmare in your life as a family. And I'm not scaring u, I'm a doctor in Haematology who manages sickle cell disease patients, so I'm being blunt here. I've lost count of the number of SS patients I've certified dead.
You gambled foolishly bro, so was your wife and I hope and pray your decision doesn't come bite u.

Naijagoodman:
This is an African problem and one would expect our medical professionals to research its solution. In Canada, nobody cares about your genotype. I've seen many Nigerians with SS children given bone marrow treatment that permanently solves the sickle cell issues. Why are our government and medical experts not looking at such an already established breakthrough? When we're serious as a country, it will show

Blake755:

It is really heartbreaking i wanted to go for the transplant but the cost of the treatment is very discouraging 💔💔

Evestar200:
🙄🙄🙄🙄