₦airaland Forum

A handout photo released by Russian Healthcare ministry (Minzdrav) shows containers with the newly registered vaccine against coronavirus in Moscow, Russia.

(CNN)A Covid-19 vaccine developed and tested in Russia generated neutralizing antibodies in dozens of study subjects, and while the vaccine often caused side effects such as fever, those side effects were mostly mild, according to data published Friday in the medical journal The Lancet.

Russia drew criticism when it announced the world's first approved coronavirus vaccine for public use in August -- even before crucial Phase 3 trials had been completed.
In the Phase 1 and 2 studies of the vaccine, which is named Sputnik V, all 76 study participants developed antibodies to the virus that causes Covid-19, according to Friday's report in The Lancet.
The levels of neutralizing antibody response were similar to the immune response that people had after naturally recovering from Covid-19, according to the study.


The researchers also looked at responses from T cells, another component of the immune system.

"[Outcomes from] the trial also suggest the vaccines also produce a T cell response within 28 days," the researchers wrote.

Larger trials needed

Scientists not involved in the study said that, while the results are a positive sign, only larger, Phase 3 trials can confirm whether the vaccine actually prevents illness with Covid-19.

"The data on the Russian vaccine studies reported in The Lancet are encouraging," said Brendan Wren, professor of microbial pathogenesis, London School of Hygiene and Tropical Medicine.


In the study, half of the participants developed fevers and 42% developed headaches. In addition, about 28% experienced weakness and 24% had joint pain.

The article did not say how long these side effects lasted but said "most adverse events were mild."

The vaccine was registered in Russia in August, before it had gone through large-scale trials. The researchers at the Gamaleya National Research Centre for Epidemiology and Microbiology in Russia received approval on August 26 to do a Phase 3 trial, which is expected to have 40,000 volunteers, according to a press release from The Lancet.


The researchers are already distributing the vaccine to high-risk groups, according to Kirill Dmitriev, head of the Russian Direct Investment Fund (RDIF), which is financing Russian vaccine research.

Gamaleya is using adenoviruses in their Covid-19 vaccines; this is the same approach used in the vaccine developed by the University of Oxford and AstraZeneca. The adenovirus delivers genetic material for the spike protein that sits atop the virus that causes Covid-19, and that genetic material is designed to generate an immune response to the virus.

Adenoviruses can cause a variety of symptoms, including the common cold. The researchers manipulate the virus so it will not replicate and cause illness.

The Gamaleya vaccine is given in two doses, and each dose uses a different adenovirus vector.

"Using two different viruses gives a theoretical advantage," said Dr. Paul Offit, a vaccinologist at the University of Pennsylvania.

Naor Bar-Zeev, deputy director of the International Vaccine Access Center at Johns Hopkins University, said in a linked comment that the studies are "encouraging but small," according to The Lancet. Bar-Zeev was not involved in the Russian study, but peer reviewed it.

Dmitriev, CEO of the RDIF, said that the trial results confirm the "high safety and efficacy" of the vaccine, adding in a statement Friday that the results are "a powerful response to skeptics who unreasonably criticized the Russian vaccine."

Mass trials begin next week

Russia has previously said it plans to begin mass vaccination of citizens in October, and the country's health ministry has said the country's frontline medical staff and teachers will be the first vaccinated.

Post-registration trials of the vaccine will begin in Moscow next week, the city's mayor, Sergey Sobyanin, said Friday.

More than 5,000 people have already signed up to participate in the trials, according to Sobyanin, who spoke during a video conference with Russian President Vladimir Putin.


Sobyanin also announced that he had been vaccinated with the first of the vaccine's two shots.

The mayor said polls suggest around half of Russian citizens are skeptical about the vaccine.

"According to the polls, around half doubt whether they need to get vaccinated for coronavirus, whether it is developed enough or not. Two months ago, there were almost 90% skeptics," said Sobyanin.

Without completed Phase 3 trials, Russia has not proven to the world Sputnik V works, though Dmitriev has previously said several countries in Latin America, the Middle East and Asia have expressed interest in procuring the vaccine.

Russia isn't the only country fast tracking its vaccine -- China approved an experimental coronavirus vaccine in June for members of its military, and in August, it emerged the country had been using the vaccine on those in "high risk" professions -- such as frontline medical professionals and border inspectors -- since July.

https://edition.cnn.com/2020/09/04/health/russia-vaccine-immune-response-intl/index.html?utm_source=fbCNNi&utm_term=link&utm_content=2020-09-04T15%3A30%3A02&utm_medium=social

Words from an elder. MOU 3 credit governor go gree hear?
Oba has said it all. No to tax collectors!!!!

Railway disaster!
Land another story!!!
Airway, that one me I no fit say.

This corn tree na wa.

E be like say na my Edo airways sure pass for me!!!

Abi Obagone wan sign MOU with the purported robbers? Coz na only MOU that 3 credit governor sabi.

Mr MOU campaign ground today at Eyaen Primary School, Uhunwode LGA!!!!

bigpicture001:
It's a pity u trust other people more than ur self... Av once won an argument about F. G not seizing lagos state allocation as publicised by tinubu....

Now you can imagine.. About 400 persons their called me daft.. And all sort of names.. Some. Of them elders.. I was close to tears.. But I stood my ground..

And got 10k as bet to back my claims.. They contributed to bet against me.. Alot of people warned me everyone can not b wrong and only me right....but because of what I know and trust that I know.. I insisted..

Low and behold they were wrong.. I didn't even say anything. I took my 20k.nd walked away....

Since then they call me aljazeera......

So if u don't mind. I don't care what crowd says

The same tin against a crowd of 8persons happened again when I told them tiger wood is the richest sport athlete... They donated money against me because of Mayweather and critano Ronaldo... Alas. I won again.....

coz you won an argument against a group of olodo doesn't mean everyone is.

I asked you a simple question, you didn't answer, that sums it all.... Have a jolly good weekend my brother!

bigpicture001:
Bro am not in the examination hall, hence will not answer ur question... Mk a point if u want to.......... You will be schocked at the level of general understanding I have of almost every subject on nairaland.........

I deliberately crafted the moniker "bigpicture" cuz lots of people don't try to see things clearly


If u follow my comments and threads, trust me, ur makes will call u "solomon"

self glorification! Haha.

I rest my case.... When someone is always defensive, just know they don't have a point....

At least from other peoples comment here, we can only agree that a lot of persons are quite aware of the US shenanigans and their gross flouting of all known international laws.

bigpicture001:
Funny! Google is not MSM.... bro check the moniker very well next time if you want to comment......


I live aljazeera on like a default in. My sitting room.. Listening and seeing news everyday for the past 24years......i know the truths ND I know wen a news is twisted.... I also know about conspiracy theorist.. Who ppl like u likes to believe in order to form sophistication......


I see the bigpicture, hence my moniker!

Like I said before now, you don't have an independent mind. Don't let your moniker deceive you, okay. Answer that simple question, how did al qaeda and Taliban came to be?

You can also read about "operation northwoods"

Operation "paper clip"

bigpicture001:
Dozens of oil tankers were suddenly destroyed with bombs on the very busy oil laden ship waterway near Saudi Arabia last year.. Who did it..?

IRAN SPONSORS terrorism in Nigeria.. You haven't heard of it... They evn threatened the country when the radical Muslim leader was arrested...

Iran shoots down her own persenger plane cuz the believe the Iranians on board are not patriotic, hence they try to flee to the west when war was looming with the US

Iran sponsors hesbollah in Lebanon with the sole aim of giving Isreal discomfort

Iran sponsors another group which constantly attacks Saudi Arabia.. ND recently blowing up 4 Saudi Arabia oil refineries....


Plz list one terror Saudi commits...

ND please Don call Yemen.. Cuz what Saudi is doing there is trying to prevent the same Iran sponsored terror group from toppling the govt. Dou with large casualties....

Iran is a terror nation.. I know u love anything anti US. But mny atimes you people do it without even deep reasoning......

I won't waste my time trying to proof anything to you. You are neck deep into the MSM bullshit...

Google can help you out on how al qaeda, Taliban et al came into existence...

bigpicture001:
The day the US influence on world happening is no more.. The closer we all are to death....

Poepl like to hail China and Russia.. But they only represent bad news...

So one as a government is terrorizing oil ships, sponsoring terrorism against Saudi, Nigeria, Israel etc... All of over the world... The US is trying to twarth it... Yet Russia and China keeps blocking them....

I pray Iran's first nuclear bomb be unleashed in China and Russia nxt

just read what you typed again.

Between Saudi Arabia and Iran who is the biggest state sponsor of terrorism? Be truthful

Russia and China represent bad news, how? Because they both have an independent foreign policy devoid of any external influence or what exactly.

Better wake up from your slumber and see things as it were. You watch too much CNN.

The US is on a decline, I don't see that trend coming to an end any time soon. The days of the US unilateralism and hegemony is over. I mean over....

Welcome to a multi polar world;

The European bloc......

The US and their willing puppet coz it seem to me the Europeans are not ready to play ball with the US anymore, no longer business as usual....

Russia and China.......

The others.......

Where is the Emotan gardens located in Edo? Abi na your back yard e dey. You and your audio MOU 3 credit governor no go kill person with all manners of lies!

Emotan gardens kill you there!!!!

Affordable kill you there!!!

fergie001:
The Portuguese Pauleta was superb and the club's record goalscorer until his record ended recently.

Heinze, left United for PSG after his bust with SAF..He wanted Liverpool and Sir insisted (to a rival? Never)...a fantastic LB....
Still hard to forgive his tumble with Evra, that gifted Kaka one of the sweetest goals in UCL history, a trip for Milan to Athens in the UCL finals (2007) which they eventually won (courtesy Inzaghi) and then his lone FIFA best player award.

https://www.youtube.com/watch?v=13damNjxiPI

Bernard Mendy was flamboyant at the RB...remembered his time on loan @ Bolton with JJ. You can't miss him at that flank.

Édouard Cisse, a very dependable CM (these days, traditionally known as a DM)....originally from Senegal, very good. I remembered his tears alongside Rothen, on that fateful night at Schalke 04 in 2004 when they lost the UCL final to Jose Mourinho's Porto.

Ronaldinho (the most skilful footballer ever) needs no introduction.

Nice one....JJ...Baba Skills.

Yepes.....The real "Super Mario"

Men don play ball abeg


They are many nowwww.....
just that the South Americans have done so well for themselves at Barca from Romario's time.

Gabriel Heinze left United for Real Madrid not PSG.

thalpy:
Ops Am in Delta state.

OK. You need to recapture again for the DOB correction...

thalpy:
Please can you give me the link?

why not, but I can only link you up if you are in Lagos.... Drop your digit or mail. I will get across.

Total annihilation of 3 credit MOU governor!!!!
Very SIMPLE!!!!

Jimasun:
It means you don't know anything about Edo.
Oshiomole raised the bar of governance in Edo.
After Professor Ali, he is the best governor in the history of Edo state

You have said it all. Oshiomole transformed Edo state to a level not seen before since the days of Ambrose Alli and Ogbemudia.... Oshiomole is not a Bini man but an Afemai man but the way the Binis loves him ehn, no be childs play.

Mr MOU dey learn work where Oshiomole dey.

Wahala ti de!

Dr Andrew Ize Iyamu, the agenda is SIMPLE!!!

MOU 3 credit governor, you see your life....

Fly wen no dey hear word, na im dey follow dead body enter inside grave....

Never again to tax collectors!!!

ogbeking:
Keep quiet, we the Edos are the ones talking. Don't hide behind a moniker to spew trash.
It will be easier for Obaseki to win this election than for Buhari to find his missing certificate.
We are in Edo, we know what's on ground.
Quote me on September 20th.

tell us your local government area in Edo state?

Emila! No level for Obagone! Obagoing!! MOU 3 credit governor!!!!

IgbalodeRaymond:
every well meaning Nigeria should stand against the bokoharam party called apc
the only party that execute soldiers but pardon terrorists and treat them with care.

Tueh!
no sane Nigeria likes APC

Emila! Tell us your local government area in Edo state?

martineverest:
lol..they Nigeria police/army should get ready for war..cos Edo people are ready for them

You and your entire family will lead from the front. No problem!

seanfer:
Oshiomhole didn’t contest any election in 2011. Try and get your facts right.

no mind that child of hate jare. Obagone is going whether legally or illegally! His fate has been sealed.

3 credit governor need to sign MOU first before him pay una o..

Wetin I dey talk sef, e be like say party of tax collectors still dey bill the MOU governor.

Or the MOU governor don carry una enter jand through one of him commissioner in crime...

Any way sha, Obagone must jam egungun for express...

The agenda is SIMPLE!!!!

Can't wait for that sweet news!!!

Following!

Kriss216:
Region grabber.
Be proud of your brown roof.

tell us the state you are from. Let's see if you are proud of your dreadful region...

Representing Edo once again. The heart beat of the nation....

The coast is clear... The agenda is SIMPLE!!!

Dem no dey telli person!!!

Obagone! 3 credit governor gone!! MOU gone!!!

Kriss216:
Face your brown roof region.

listen up. I'm from Edo, Edo through and through!!!

IPOB, face your potopoto region!

MOU governor must go! The most useless governor of Edo since Lucky Igbinedion.

Never again to tax collectors!!!

Kriss216:
Oshiomhole and APC should go and sit down!

Edo is not Lagos.

God bless Edo
God bless Obaseki



Shame on Ambode!

shame no dey catch you? I doubt if you are from Edo?

thalpy:
like how much

I paid 20k just to facilitate things. Not funny bro... on top the 15k remitta... All because of international passport. 35k altogether.... In 10 working days it was corrected and rectified.. Lagos precisely..

jacquincy:
go to the nearest enrolment center with the following.

-The NIN slip
-original Birth certificate (fixed)
-Evidence of Remita payment in favour of national id commission (#15,000)
-Official application to the D.G requesting a change of your DOB
-and some or all of the documents listed below...
1. WAEC (must display dob)
2. NECO
3. Voters card
4.Drivers license
5. first school leaving certificate
6. any document that can substantiate your claim

Do also note that the fee paid for this service is non-refundable and the commission reserves the right to dismiss your application if found to be false or if you do not provide enough source documents to back your claim

You forgot to tell OP, that he has to bribe before things will be done. Very expensive bribe. If he doesn't bribe, he will wait forever. Talking from experience.