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What is the lease agreement

Call the number or contact me via WhatsApp.

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Leicester city defying all odds. EPL CHAMPIONS ELECT.

Here is an indepth analysis of the common forms of genotype. All intending couples should take note. It is better to be safe than sorry.

The AS AC SC SS and CC genotype.
What you have in your blood are cells, the most predominant of which are called RED BLOOD CELLS (RBCs).
These cells contain within them HEMOGLOBIN, a substance without which the RBCs are invariably useless.


This hemoglobin itself is composed of 2 parts: a heme (don't bother yourself, this basically is a complex Iron-protein complex) and globin (2 pairs of protein chains, this is the important part).
There are 2 alpha and 2 beta globin chains - the pair, and there is a normal way the chains are supposed to be structured.
The error happens when a protein substitution occurs in any one of these chains - but particularly in the globin chains (First of all, you have to understand that amino acids are the building blocks of proteins - so if amino acid 'x' is the normal, an abnormality occurs when instead of 'x' at a particular location along the chain, you have 'y'.)


That is as simple as it gets. These errors of substitution are given the big name of 'THALASSAEMIAS'. In reality, a substitution will occur at any point along either the alpha or beta chains but for the purposes of simplicity and to answer your question, we focus on the genotypes AS, SS, AC.

Genotype AA: At position 6 of both globin chains,the amino acid is GLUTAMATE

Genotype AS: At position 6 of one globin chain is GLUTAMATE and at position 6 of the second globin chain, you have VALINE

Genotype SS: At position 6 of both globin chains, the amino acid is VALINE

Genotype AC: At position 6 of one globin chain is GLUTAMATE and at position 6 of the second globin chain, you have LYSINE

There are different types of Hemoglobin; among them are Hemoglobin A, Hemoglobin S and Hemoglobin C.
Hemoglobin C is very rare.

Everyone must have a pair of these hemoglobin in their blood, each inherited from both parents.

The pairing might be in any of the following formations: AA, AS, AC, SC,SS OR CC.
A man with AA can marry any one without any problem (medically); likewise the woman.

How do people get their genotypes?
Simple, from your biological parents.
If papa bomboy has a genotype AA and mama bomboy has a genotype AS, which genotype do their children have?
What we do in theory is this, you cross each of those letters so that you have AA, AS, AA, AS? Therefore, for each pregnancy and each bomboy they delivery has a 50:50 probability of being AA or AS.

What if their genotypes were AA (for papa bomboy) and SS (for mama bomboy); you do the crossing again: AS, AS, AS, AS. Therefore, it is very UNLIKELY that any of their children will have a genotype outside of AS.
You will see that I have used the word unlikely because poo happens. They might end up having a child who is either completely AA or SS but whatever happens, a child's genotype is never outside of the parents. Eg. a man and woman who are both AA can never have children with genotype starting or ending with 'S'. If it happens, either your landlord or next door neighbours are highly involved (just kiddin Oluwa isn't involved').
So for you to get C, you must have a parent who carries a 'C' in his or her genotype.
Likewise the S must have a parent with S genotype
One more thing: Are there any clinical features of Hemoglobin C like Hemoglobin S?

In the case that you're AC, well the good news is that MOST TIMES THERE ARE NO SYMPTOMS, but occasionally, there is JAUNDICE.
THE BEST PART IS THAT YOU CAN LIVE A NORMAL LIFE WITH AC!!!

And just for the case of mentioning genotypes, you could have:
Regular Genotype: AA (healthy as healthy can be)
Traits: AC, AD, AF, AG, A+FAST, AE and AS (not associated with any clinical signs, symptoms or syndromes - they as relatively as healthy as AA)
Genotypes associated with clinical features: SS, SC, CC (are associated with clinical signs, symptoms and syndromes)

•Please note that the marriage thing is this, we really don't know what the recent trend is but the important thing is to make sure your genotype of you and your partner don't match up in a way as to produce children with SS, SC and CC.
These children only suffer for nothing!!!
You can't even begin to compare the differences in severity between CC and SS disease.

Symptoms of Hemoglobin C dsx (CC)
Most people do not have symptoms. Occasionally, jaundice may occur.

Complications of Hemoglobin C dsx
Sometimes, they may experience the following:
Cholelithiasis (gall stones that may require treatment)
Splenomegaly (big spleen)
Angloid streaks (causing poor vision)
Aplastic crises (due to viral infection): episode of severe anemia

Treatment
There is no treatment. Folic acid supplementation is required to help the body with red blood cell production and improve symptoms of anemia.

Prognosis
Note that unlike the Hemoglobin S dsx (SS), pxts with Hemoglobin C dsx have a normal life expectancy,

Before we forget, what about SC genotype?
Please note the following:
AA: normal pxts
AS: don't show any symptoms
SS: sickle cell disease (sicklers)
AC: don't show any symptoms
CC: described above
SC? This condition is associated with recurrent anemia (breakdown of red cells in the blood vessels) and pain crises (vaso-occlusive crises). Some may also experience aseptic necrosis of the thigh bone (femur).

Summary is that it is bad,
One thing you must understand is that in terms of geographic distribution, the hemoglobin C allele is found at the highest frequencies in West Africa and it has been associated with protection against malaria.
A good number of people have the C allele but are unaware of it.
Also note that most people with the AC genotype show no symptoms,

PLEASE NOTE THIS AND HELP SHARE WITH A FRIENd
A man or woman with AS or AC or SS or SC or CC (very rare) cannot marry each other, if they want to avoid SS or SC.
They must marry a partner with AA, if they don't want to born a child with Sickle call syndrome.
If AS or AC marry each other, they have 25% chance of having a sickle child at every birth. If they marry SS or SC, they have 50% chance of having a sickle cell child at every birth.
Please note all their kids could be AS AC or AA.
If SS or SC marry each other, it's is nothing other than a terrible disaster.
All their children will have Sickle cell
SC and SS are almost the same only that SS suffers more severe crisis than SC carrier. You might not notice the presence of the disease on the body of SC carrier, unlike in SS.

Solution
The only thing that can change the genotype is an intentional act like BMT.
Bone Marrow transplant technology has been proven to be the only permanent cure to SS SC and CC; however, it is new, very expensive and cannot be done in any part of Africa, and carries some risks.
Naturally, environment or time cannot change genotype.
Please Note: Divine Miracles can change it as well - it has happened in so many part of the world.
Again, some SS carriers may start experiencing crisis at late age (as late as 40s).
If these sets of people go for test in a quack lab, definitely the lab technician will assume AA or AS since the person is not having the symptom.
Later in life it will become obvious when the symptom have come up, and another lab technician will report SS.

To all unmarried folks, please know your genotype and that of your spouse.
Only people with AA genotype can marry people of other genotype AC AS SC SS or CC without any medical complication.

Culled from Laumsites Ywc facebook page.

Happy Birthday.

This is called thinking out of the box. PMB being an ardent reader of our national dailies may consider him. Wishing him the best of luck.

Details of a petition by a Senior Legislative Assistant against his boss, a serving senator, which has been before the Economic and Financial Crimes Commission (EFCC) since March 2015, provide an insight into how unnecessary the average N150 billion annual budget on the National Assembly since 2010 has been. With documentary evidence, the senator’s aide, a doctorate degree holder, enumerated how, in an attempt to retire the quarterly funds and other allowances he received from the National Assembly Commission, the senator forged documents and allocated spurious and laughable figures to expenditure never incurred.
The Senior Legislative Assistant claimed to have written the petition to the EFCC to compel the senator to pay him his entitlements for serving his boss for three years. In one of the retirement documents for the third quarter in 2012, for instance, the senator claimed to have spent N10 million on travels for 21 days. Those he claimed to have travelled with included his Senior Legislative Aide, a Legislative Aide, a Legislative Assistant, his Secretary, his driver and his police escort. Each of them, the senator claimed, had travelled with him for 21 days in that quarter. Also, the cost of maintaining three vehicles in one quarter was put at N1.5 million. It cost N788,500 to fuel the three vehicles in that quarter, and for contingencies, the senator claimed to have spent N6 million. The total sum for the subhead of this overhead allocation was put at N10 million.
As if he contradicted himself, within that same quarter, the Senator, in another retirement of a cash advance of N8 million, claimed to have travelled outside the country for 30 days. He claimed to have travelled with his Special Assistant and Personal Assistant who received $600 per day, $425 per day and $381 per day for 30 days respectively.
As if the above are not enough falsehood and forgery, the retirement of the N51 million paid to the senator in the third quarter of 2014 came with shocking claims. The senator claimed in the document that for three months, he spent N10 million on local travels and transportation. Within the same period, he claimed to have spent N8 million on foreign travels. Other items that would shock the reader include the sum of N1.8 million spent on newspapers and magazines; his vehicles maintained with the sum of N1.5 million and maintenance of office equipment with the sum of N1.8 million; while the maintenance of computer and IT cost another N1.7 million.  The senator’s retirement claims showed evidence of forgery that an amateur forensic expert would detect even in his sleep. The distinguished supported the retirement with over a hundred receipts, from restaurants, to hotels, to car service centres, etc, all bearing one handwriting, signed in the same way, addressed in the same way, and figures written in the same manner.
Even the constituency projects, which are supposed to be carried out on behalf of the senator by a government agency, were cornered by the senator, executed by a company he chose. The documents attached to the petition indicated that the projects may never have been carried out.
The above facts give a bite to the outcry in the country against the huge resources voted for the National Assembly in the annual budget. Data mined by our reporters indicated that from a budgetary allocation of about N19 billion in 2000, the National Assembly now budgets for itself and average of N150 billion annually, an increase of over 700 per cent. The official emoluments of senators sketched by the Revenue Mobilisation Commission are as follows: Basic annual salary of N2,026,400.00, duty tour allowance put at about N32,000, and an estacode of $600 per night. As for House of Representatives members, each of them is entitled to N1,985,212.50 annual basic salary, N21,000 duty tour allowance and $550 estacode per night. In addition to this, each senator is entitled to N51 million per quarter, while the House of Representatives members receive N36 million every quarter. From the quarterly allowance alone, each senator earns N546,000 per day, while the House of Representatives member earns N394,520 per day, though the lawmakers do not work every day of the year. In 2012, the United Kingdom-based The Economist claimed that, with the kind of funds available to the Nigerian lawmakers, they are the most paid in the world.
Also, considering the annual N150 billion budgetary allocation to the body since 2011 when the 7th Assembly was inaugurated, it becomes apparent that the body has received at least N600 billion, but has passed 106 bills since the Jonathan administration came to power in 2011. That means on the average, the lawmakers spent N5,660,377,358.00 to work on each bill to pass it into law. It is not clear in the incoming government of Muhammadu Buhari will be able to cope with such huge budgets for the lawmakers, considering his anti-corruption stance and the dwindling revenue from crude oil, the country’s economic mainstay.


LAWMAKERS PRESSURIZE EXECUTIVE FOR FUNDS:
Mr Auwal Ibrahim Musa Rafsanjani the Executive Director, Civil Society Legislative Advocacy Centre (CISLAC), told Sunday Trust that corruption is one of the reasons why lawmakers cannot perform their functions dutifully. According to him, “When they go for oversight functions, some of them try to use their positions to get what is not supposed to be theirs. During the budget defence, some of them also are alleged to have been demanding for some money to pass a particular item in the budget.  Sometimes, in the case of some of the ministries, they ensure that there are some items in the budget of their ministries or parastatals that are not part of their original plan. But they put it in the budget. Later, they (lawmakers) will ask them to pull out that aspect for them. We also hear the allegation of some people who have gone to the National Assembly for confirmation as Ministers or for a particular position. You remember the case of Mallam Nasir El-Rufa’i in 2003, when he alleged that some legislators demanded money for his confirmation. You also heard the case of Honourable Herman Hembe against the former Director General of the Securities and Exchange Commission, Ms Arunma Oteh, over bribery allegation, which is in court. You also hear the case of Farouk Lawan, who is also in court on the bribe scandal over the oil subsidy issue. So, there are quite numbers of issues that are known to the public. There are other ones that are not known to the public.”     
Malam Rafsanjani added, however, that  “we believe and know that there are many legislators who are not engaged in these malpractices. But what happens over the years is that there is unnecessary solidarity by legislators. Once there is an established case of corruption conducted by one of their colleagues, with the exception of the Farouk Lawan scandal, I think in most of the cases, there were some attempts to either cover up or do solidarity on them. But the National Assembly needs to do something. In some instances, there were allegations of outright demand by legislators before they passed legislations. For example, we heard allegations that some powerful companies, like oil companies, coming to bribe members in order to take one action or the other.”

OBASANJO’S MONETISATION POLICY CAUSED BLOATED NASS BUDGET - NA’ABBA
A former Speaker of the House of Representatives, Alhaji Umar Ghali Na’Abba, in an interview with Sunday Trust blamed the administration of former President Olusegun Obasanjo, which introduced monetisation policy for the hike in the earnings of lawmakers.
According to him, “Before 2005, that was not the situation. This started because of monetisation. In that year, Obasanjo, in his own wisdom, decided that everything about governance should be monetised. He directed that all houses belonging to the federal government be sold. So, they were sold. But you need these houses to shelter legislators and the civil servants. That is why the expenditure for the legislators and civil servants became over-bloated. Today, renting the kind of property that housed a minister will cost about N30 million because you have to furnish it and do many other things. I’m told that when a new minister is appointed, he is given about N100 million to get accommodation and furnish it. Then, he will be given money for vehicles. So, when you add up, it is a lot of money.”
The former Speaker argued further that “The legislature, by its nature, is a money guzzling institution. If, for example, there is a motion on flood in Kano and I move the motion for the government to do something about it and it is accepted, the House authorises that a particular committee should go to Kano and assess it. That will cost a lot of money. If you have five of such motions in a day, you sit for four days in a week and you have 20 motions like that, you have to spend almost N50 million, for example, in the least. This happens on weekly basis, which is just one aspect. You have committee staff, among which is the secretary, who is the counterpart of a permanent secretary in the ministries. You have to have other staff of the committee. So, all the committees have counterparts who supervise the directorate on behalf of the committees. Both the Senate and the House of Representatives will have such committees. People don’t know all of these things. Legislative work is not just sitting in plenary. Most of the works are done in offices. If you go to the US, for example, it is rare to see up to 50 members sitting at a time for a legislature that has over 400 members. They have CCTVs in their offices. From there, they watch what transpires on the floor of the House. Sometimes, you enter and see only the Speaker and one member talking and the person sitting on the Speaker’s chair may not be the Speaker.  The only time you see them cluster is when there will be a vote. But here, people want to see themselves on television.”
He added also that “Motions moved in the National Assembly are very expensive. And they are more or less advisory. The work of the legislator is not restricted to the chamber. There are lots of works. People have not been exposed to lots of the works the legislators do. That is why they are concerned about the budget of the National Assembly. But before I make a final comment, let me say that the people must be determined on what they want with their National Assembly. I don’t believe legislators should be in a situation where they are not being well taken care of. Reasonably, you must take care of your legislator because anybody who will make laws for you should not be allowed to be distracted by anything. A lot of times, noise is made that legislators are going about chasing contracts. This situation should not be allowed."

CALL FOR CUT IN EXPENDITURE ON LAWMAKERS:
Rafsanjani believes that the incoming administration should look into the huge expenditure on the legislature and do what is appropriate to reduce it. He told Sunday Trust that “It is important for the incoming administration to look into the fraudulent idea of public officers allocating resources to themselves, sometimes, bogus allowances. The Revenue Mobilization Allocation and Fiscal Commission (RMAFC) is supposed to be responsible for allocating wages to public officers. But what happens is that, with the autonomy from the National Assembly, for example, they now create many allowances for themselves. It is not sustainable. It is too much. It is too bogus. That is not done in the interest of the country. So, as a way forward, the National Assembly members and the executive members, who are political appointees, should reflect and ensure that they do not have allowances, salaries or wages that are outrageous. They can actually have reasonable amounts to enable them do their work effectively.”
Also, a lecturer in the Faculty of Law of the Ahmadu Bello University (ABU), Zaria, Bello Ibrahim Jahun, told Sunday Trust in an interview at the weekend that the incoming lawmakers should face the business of making laws rather than looking for money.
According to him, “The agenda for the incoming National Assembly shall be lawmaking and lawmaking alone, although, there are certain auxiliary functions that they also ought to do along with the executive. For example, in the appointment of ministers they have to confirm that a particular person has made all the required qualifications before he becomes a minister. That process is not lawmaking but it is something that has to do with the sanity of the system and there are laid-down procedures and the National Assembly is empowered to make sure that under the principle of check and balance that the Executive has complied with the rules on the appointment of ministers.
There are other offices where the president cannot make appointments without the consent of the National Assembly. For example, the confirmation of the Chief Justice of Nigeria has to sometime go through the scrutiny of the National Assembly, among others. This is really the function of the National Assembly to make law for the nation.”
The law lecturer also argued that the lawmakers should not bother themselves about constituency projects. He said, “Development or constituency projects have nothing to do with lawmaking, but you may find that the electorate are asking their legislator what he has brought to the constituency. This is why, perhaps, they went on to develop the theory of constituency projects. However, the constituency projects may have a constitutional flavour of doing something to improve the lots of the people. But these are things that are within the powers of the Executive; in the states the governors and at the federation the president.  In other words, execution of development projects can only be done by a local government chairman, because there are areas that are described under schedule 4 of the constitution, or the governor of a state or the president. When budgets are made, you find that there are capital or recurrent provisions. All these things are done by the executive. I think it is the political pressure rather than the law that led to the creation of constituency projects.”
The Chairman of the House Committee on Finance, Abdulmumini  Jibrin, while speaking to Sunday Trust on phone at the weekend said the leadership of the House of Representatives under the Buhari  administration would  have zero tolerance for corruption.  “We will also ensure cut in governance because of  dwindling revenue due to the fall in oil price, and the National assembly should not be an exception”, he said.  Jibrin said the Eight Assembly won’t  be a puppet to the Executive but will cooperate with it and the other arms of government to succeed. “Our leadership will create the atmosphere to relate well with the Executive in order to put things right”.  He insisted there won’t be need any more for any member of the House to go to the ministries to look for favour. However, he said, “The National Assembly will be strengthened and reformed. Members will be educated on public hearings and capacity building to help them discharge their responsibilities,” Jibrin said. 

Source: Sunday Trust

The Biu to Abuja got me cracking. Nollywood do the needful.

The last time I checked communication is incomplete till recipients of a message are able to identify the sender’s intent, take into account the message’s context, resolve any misunderstandings, accurately decode the information and decide how to act on it. Why can't we communicate by using the simplest of words?

It is not always greener at the other end but I'll rather take the risk than stay put with a 75k job. @Op after a couple of years you'll realize your risk paid off. You can live the American dream. A word they say is enough for the wise.

Result fever

Do we still have CPC in Nigeria? Op you can do better.

This postponement is uncalled for. The february 14th date was scheduled a long time ago and all the stakeholders were privy of the date. I believe there was enough time for putting everything in place. With a week to election it was postponed. Postponing the election say a couple of months ago would have been reasonable. May God's will be done.

For the first time in its history WhatsApp is coming to your desktop.

The update has just been announced by new owners Facebook and lets users access their account via the Chrome browser.

To connect you simply head to the WhatsApp webpage and scan a QR code using your smartphone.

You then get full access to your messages and all conversations automatically sync with your phone.

However, there is one major catch as the web based service is currently only available to Android and Windows owners.


WhatsApp say "Unfortunately for now, we will not be able to provide web client to our iOS users due to Apple platform limitations,"

That means iPhone and iPad owners will have to stick to messaging from their phones.

WhatsApp was purchased by Facebook for $19billion and latest figures show it has over 700million users.

After the purchase last year, Facebook founder Mark Zuckerberg, famously said that $19billion was a bargain.

GEJ and GMB supporters should shun violence.

I think I read this story. He used a skin whitening pill called glutathione. I do not support skin whitening but this pill is a powerful antioxidant and safe to an extent.

A Congressional communications director resigned today after making disparaging comments about Sasha and Malia Obama on Facebook.

Elizabeth Lauten, the communications director for Rep. Stephen Fincher, R-Tenn., last week criticized the girls' demeanor during the annual White House turkey pardoning ceremony, writing on Facebook: "Dear Sasha and Malia, I get you’re both in those awful teen years, but you’re a part of the First Family, try showing a little class.

"At least respect the part you play. Then again your mother and father don’t respect their positions very much, or the nation for that matter, so I’m guessing you’re coming up a little short in the ‘good role model’ department. Nevertheless, stretch yourself. Rise to the occasion. Act like being in the White House matters to you. Dress like you deserve respect, not a spot at a bar. And certainly don’t make faces during televised public events."





Lauten was widely criticized across social media for her comments. She then deleted her original post and wrote an apology on Facebook that she sent to ABC News.

"After many hours of prayer, talking to my parents, and re-reading my words online I can see more clearly just how hurtful my words were," Lauten wrote. "I'd like to apologize to all of those who I have hurt and offended with my words, and I pledge to learn and grow (and I assure you I have)from this experience."

In a phone call, Lauten choked through tears as she told ABC News that she had resigned Monday morning. She refused to discuss the circumstances surrounding her resignation, instead pointing to her Facebook apology as her comment on the incident.

White House spokesman Josh Earnest said he was “taken aback” by Lauten’s criticism of the president’s daughters, adding that all public and political figures must “choose our words wisely.”

“I was taken aback that there was a political operative on Capitol Hill who took the occasion of the Thanksgiving event to criticize the first family,” Earnest said, marking the first official comment from the White House on the incident.

Asked whether the White House believes in principle that the first daughters should be “off limits,” Earnest said, “A principle like that is pretty much common sense.”

“Me and all the people in this room have ability to speak publicly ... and we choose our words wisely,” he said. The incident is “a reminder of how important that is.”

Earnest said Lauten’s Facebook apology “was the appropriate thing to do” although he didn’t comment directly on her resignation.