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3 PARENT BABIES. The Adventure Of The Spermatozoa, The Egg And The Mitochondria. - Nairaland / General - Nairaland

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3 PARENT BABIES. The Adventure Of The Spermatozoa, The Egg And The Mitochondria. by Nobody: 11:11pm On Feb 03, 2015
Three-parent babies are human offspring with three genetic parents, created through a specialized form of In vitro fertilisation in which the future baby's mitochondrial DNA comes from a third party.[1][2][3] The procedure is intended to prevent mitochondrial diseases including muscular dystrophy and some heart and liver conditions.[4] It is the subject of considerable controversy in the field of bioethics. The procedure is currently illegal in all countries, however in the United Kingdom[4], a draft law was debated in February 2015.

The UK is now set to become the first country to introduce laws to allow the creation of babies from three people.
In a free vote in the Commons, 382 MPs were in favour and 128 against the technique that stops genetic diseases being passed from mother to child.
During the debate, ministers said the technique was "light at the end of a dark tunnel" for families.
A further vote is required in the House of Lords. It everything goes ahead then the first such baby could be born next year.
Proponents said the backing was "good news for progressive medicine" but critics say they will continue to fight against the technique that they say raises too many ethical and safety concerns.
Estimates suggest 150 three-person babies could be born each year.
Prime Minister David Cameron said: "We're not playing god here, we're just making sure that two parents who want a healthy baby can have one."
Life-saving
The method, which was developed in Newcastle, should help women like Sharon Bernardi, from Sunderland, who lost all seven of her children to mitochondrial disease.
Ms Bernadi said was "overwhelmed" by the decision.

Media caption
Sharon Bernardi, who lost seven children to a genetic disease: "I'm just overwhelmed"
Mitochondria are the tiny compartments inside nearly every cell of the body that convert food into useable energy. They have their own DNA, which does not affect characteristics such as appearance.
Defective mitochondria are passed down only from the mother. They can lead to brain damage, muscle wasting, heart failure and blindness.
The technique uses a modified version of IVF to combine the DNA of the two parents with the healthy mitochondria of a donor woman.
It results in babies with 0.1% of their DNA from the second woman and is a permanent change that would be passed down through the generations.


1) Two eggs are fertilised with sperm, creating an embryo from the intended parents and another from the donors 2) The pronuclei, which contain genetic information, are removed from both embryos but only the parents' are kept 3) A healthy embryo is created by adding the parents' pronuclei to the donor embryo, which is finally implanted into the womb

1) Eggs from a mother with damaged mitochondria and a donor with healthy mitochondria are collected 2) The majority of the genetic material is removed from both eggs 3) The mother's genetic material is inserted into the donor egg, which can be fertilised by sperm.

Debate
In the Commons debate, Public Health Minister Jane Ellison told the House: "This is a bold step for parliament to take, but it is a considered and informed step.

Terms
In vitro fertilisation: (IVF) is a process by which an egg is fertilised by sperm outside the body: in vitro ("in glass"


http://en.m.wikipedia.org/wiki/Three-parent_baby
http://m.bbc.com/news/health-31069173

Re: 3 PARENT BABIES. The Adventure Of The Spermatozoa, The Egg And The Mitochondria. by Young03(m): 11:16pm On Feb 03, 2015
I watched dt on BBC news 2day

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