A PhD student in the Department of Chemistry, University of Ilorin, Misitura Arowona, has developed a drug that promises to be potent in the treatment of tuberculosis, an infectious disease that usually attacks the lungs.


The University of Ilorin Bulletin, on Monday, stated that the student, who is being supervised by Prof. Joshua Obaleye, former Dean, Faculty of Science of Unilorin, is currently undergoing a sandwich fellowship at the Faculty of Science of The Maharaja Sayajirao University, Vadodara, India.


According to the publication, the metal attached anti-TB drug developed by Arowona, has improved the efficiency of the anti-TB drugs compared to normal drugs that are consumed globally.


“The country is ranked seventh among the 30 high TB burden countries and second in Africa and the problem of TB in Nigeria has been made worse by the issues of drug-resistant TB and the HIV/AIDS.


“It is estimated that about 407, 000 people in Nigeria have TB in a year,” it said.

The publication explained that Arowona, who is in Vadodara for a year-long project, said, “Earlier studies have proved that when a metal is attached with a pharmaceutical, it increases the efficacy of the drug.

“Taking a cue from cisplatin, an anti-cancer drug, whose efficacy improved after applying platinum as metal, the scholar worked on multiple metal-based drugs to see whether the efficiency of anti-TB drugs can be increased by attaching metals to it”.

Also quoting a Professor of Chemistry, Rajendrasinh Jadeja, of Sayajirao University, India, the Nigerian scholar used metals like ion, cobalt, copper and zinc to prepare the metallodrugs.

“The drugs, which have been developed, include ciprofloxacin HCl, ofloxacin, pyrazinamide and moxifloxacin HCl. Presently, there is no metal-based anti-TB drug available in the market.

“When we compared the metallodrugs with the original anti-TB drugs, the metallodrugs were more effective.

“We did in-vitro test against bacteria. The metals we have chosen are non-harmful to human beings.

“Also, we found that of all the metallodrugs, the copper complex of ciprofloxacin is most effective.”



https://punchng.com/unilorin-phd-student-develops-new-anti-tb-drug/

That's a very good moves, nigeria got talent, I pray everybody got to display his

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YorubaAmaka again

Don't rejoice yet

For the drug to be seen as a cure...it has to go through invivo, invitro(our man has done the invitro testing), animal testing and then human testing...phase 1 to 3.

If he gets the funding...he would have his drug on the market 10 years from now.

The gold standard is the drug

1.Has to be proven to clear TB in human patients better than the exisitng theraphy

2.Has to do so with minimal side effects

N.B: What he is doing is attaching metals to the (already existing anti-TB )drugs to see if it improves efficacy in treatment. In other words, he is working on a way to see if drug uptake and action can be improved. Even then, the glod standard is when he does a large scale RCT to see if his mettalodrugs work better than the ordinary drugs.

Hope Nafdac won't frustrate him? A lecturer of ours back then who developed Siklavit for Sickle cell patients went through so much rigor to get the drugs approved till Rigor Mortis met him... He died before the drugs was finally approved

Better by far

If it of no use to cow the president is not in support.

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OAU can never can. But they can take pride in delaying PhD students for 10years. useless school full of senile saddists oi the name of lecturers. double tueh

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Hope he has considered the effect of metals on kidney function. Cisplatin is used as short course chemotherapy agent.

CIA will soon visit this one

crazyABO:
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No mind the mad man

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Continue

DameB:
Hope Nafdac won't frustrate him? A lecturer of ours back then who developed Siklavit for Sickle cell patients went through so much rigor to get the drugs approved till Rigor Mortis met him... He died before the drugs was finally approved

It takes years for a drug to go from development to actually appearing on the market.

You have to determine the safe dosage, the side effects, whether it works better than the existing drug, among other things. All that takes years....especially if the funding is adequate.

Nice moves


For stubborn STD check my signature.

y

Good news. Let me read and see the source first.

Nice to add value to the existing ones. It's not easy. Good one from our own.

people can lie in heaven. in d next couple of years u won't hear anything about it anymore

well done mistura.....#unilorin#better by far#my Alma mater