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Help! His Genotype Is AA And His Wife's Genotype Is AS But Their Daughter is SS - Health (4) - Nairaland

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Re: Help! His Genotype Is AA And His Wife's Genotype Is AS But Their Daughter is SS by omolafetuyi(m): 11:47am On May 12, 2015
lipsrsealed

Village pple @wrk
Re: Help! His Genotype Is AA And His Wife's Genotype Is AS But Their Daughter is SS by sendmeonly(m): 11:47am On May 12, 2015
Demichaels:
My friend's 10 year Marriage is about to collapse.

His, my friend's genotype is AA and his wife's genotype is AS but their 4 year old daughter has been confirmed to have SS genotype by not less than 4 different medical experts. He confronted the wife and accused her of infidelity but she vehemently denied having any affair with another man. In other to prove her wrong, my friend subjected the little girl to a paternity test and there he got the shock of his life - the result showed he actually is the father of the girl. At first he accused the doctor of compromise because he is their family doctor and somehow relates to the wife. He then decided to go to another hospital to prove the paternity of the girl child there and then he got another shocker - the first result was actually correct. As It stands, my friend has consulted more than five other doctors outside the state of his residence and all Confirmed that the girl's genotype is SS and he actually is the father of the child despite his and the wife's genotype being as stated above. Even the doctor's are confused by the results as it negate conventional medical norm.

My question now is, experts in the house, is there anything that can lead to such unconventional biological flaw? Under what condition can AS and AA couple have an SS child? Can mutation lead to such condition? My friend insists on divorce because he doesn't believe the wife. Should he go ahead based on what we all know about genotype?


Please I need matured advice on this. This is a REAL LIFE SITUATION AND NO FICTION. I WOULD HAVE MENTIONED NAMES AND ADDRESS OF THE COUPLE BUT I DON'T HAVE















It could be as a result of gene from fourth filial generation if you get what i mean...its not unconventional it does happen,the same way you see two short couples giving birth to a tall child etc




THEIR PERMISSION YET. THIS IS HAPPENING RIGHT HERE IN PORT HARCOURT OLD GRA WE'RE LIVING
Re: Help! His Genotype Is AA And His Wife's Genotype Is AS But Their Daughter is SS by steams: 11:48am On May 12, 2015
He should do a DNA test on him and the child, DNA don't lie.,and the wife must not know about it so as not to influence the result.
Whatever the outcome. RELIGION WITHOUT SCIENCE IS BLINDNESS
Re: Help! His Genotype Is AA And His Wife's Genotype Is AS But Their Daughter is SS by Ese144: 11:48am On May 12, 2015
Has he done a DNA test?
Re: Help! His Genotype Is AA And His Wife's Genotype Is AS But Their Daughter is SS by dorox(m): 11:49am On May 12, 2015
There is a very rear condition called chimerism which I think the father of the girl might have.
Basically, the man has two different dna and depending on the organ or part of his body that is tested, the result can be totally different.
You can google chimerism for a detailed explanation.

6 Likes

Re: Help! His Genotype Is AA And His Wife's Genotype Is AS But Their Daughter is SS by Texcoco(m): 11:49am On May 12, 2015
There is an elaborate scam going on here and the man is the sucker......the chances of an AS/AA getting a haploid SS offspring is as bright as our dream wedding with Stella Oduah....
Re: Help! His Genotype Is AA And His Wife's Genotype Is AS But Their Daughter is SS by Nobody: 11:50am On May 12, 2015
all I smell is away match grin grin
Re: Help! His Genotype Is AA And His Wife's Genotype Is AS But Their Daughter is SS by MistadeRegal(m): 11:50am On May 12, 2015
Pay attention to my story.
I am the third child but the first son. My sisters look exactly like my mum and dad respectively. My younger brothers look like my parents also respectively while I am different. My dad never treat me different from others and whenever he's scolding me, he always say, "I am your father and I won't watch you ruin!" Years later, I recalled as I grow taller, my grandmother(dad's mum) came visiting. And when it's morning, I went to greet her our native way. She pulled me up and began our lineage pedigree, I didn't look up at her and then she raised my head up and gave me the first shock!...She called my dad sharply and said to him with her eyes wide open, "This is the exact figure of your father!"
Since then, she always call me her husband.

Now, two years ago, my uncle(dad's elder brother) died. We all went to his home town. Dad took I and my uncle's son to greet some elders. We went round and came to the chief's(Baale) house where we all were assembled and he started eulogising us for the dead. This was where I got abother shock. I have never met this old man ever before but to my surprise, as many as we are there with him, while he was still speaking, I looked up, he paused and pointed at me saying same words, "Of all those here, ONLY YOU took after the beauty of your grandfather!" Everyone turned and stared at me! Some of my cousins whispered, "A je pe grandpa fine gan niyen o!"(That means grandpa is very handsome!) Then he(Baale) continued hus words....

Now what am I trying to tell your friend, if DNA proves he is the father of that girl, she could have taken after any of his grannies. He should never doubt his innocent wife and paint her a colour she never deserves because for the fact that I did not look like my dad or mum does not make me a bastard. Note.

6 Likes

Re: Help! His Genotype Is AA And His Wife's Genotype Is AS But Their Daughter is SS by SLYBABA(m): 11:50am On May 12, 2015
still loading undecided
Re: Help! His Genotype Is AA And His Wife's Genotype Is AS But Their Daughter is SS by Missonas(f): 11:50am On May 12, 2015
femi4:
Its impossible, both of them are AS, they should just divorce. The man is lying, he is not AA

Chai femi scatter grin they should jst divorce.thkGod say d op is nt the person on question o

1 Like

Re: Help! His Genotype Is AA And His Wife's Genotype Is AS But Their Daughter is SS by donLEXY(m): 11:51am On May 12, 2015
It is not 100% impossible, though extremely rare. And we need to know how old the baby is at the time of testing. Let us assume all test done are 100% correct, the only thing I can say about the situation is that the baby got two S gene from the mother( when you talk about mendel's law of inheritance, we always have exceptions to the rules). Hemoglobinapathie is more common in West Africa and Asia. All other phenotypes are c,d,e,o and probably three more that I canno remember @ heart (pls don't tell my professor lol), some are further divided into different cities where they were found like HgDharlem. Collect blood samples from all three of them in an Heparin tube and send to an Hematology lab going to agbabiaka community hospital and lab will not help in this case

3 Likes

Re: Help! His Genotype Is AA And His Wife's Genotype Is AS But Their Daughter is SS by Gozzzy(m): 11:51am On May 12, 2015
It can occur, but very rarely. There is a whooping 12.5a percent chance of occurence.
Btw, fvck mz jackbuaress.

1 Like

Re: Help! His Genotype Is AA And His Wife's Genotype Is AS But Their Daughter is SS by biodemetrik: 11:51am On May 12, 2015
I suggest he goes for a more molecular test for genotype. The conventional methods may not solve this issue. RFLP restriction fragment length polymorphism or the PAGE pulse field gel electrophoresis

2 Likes

Re: Help! His Genotype Is AA And His Wife's Genotype Is AS But Their Daughter is SS by bettercreature(m): 11:51am On May 12, 2015
funshiba:


Hmmmm.... I got scared when i saw this post.... Its with heavy heart I say this is happening in my young marriage....My spouse is AA im AS. We had our baby in America this year they told us this, We asked for a recheck and it was almost same thing.

We decided to come to run our test in Nigeria, A test and a re-run says the same SS. The hospital advised we check again in few months as the infants undergo changes and the result cannot be confirmed.

We will wait till she is 6 months to 1yr old. But you dont have an idea of how scared i'm. I discussed with a medical consultant friend and he told me it is impossible that I should worry and check when she is one. but I'm scared to death and pray about this everyday. Medicine is abit funny cos I dont know possible this is medically and I dont want my only kid to be an example of such. Pray for us. Its not a good thing to happen.

Note that we are 100% sure of our status and had several rerun of test, I also trust my spouse with all my heart, Besides she is the AA.

I will advice this family that made the post to wait and not scatter the home cos of this. Accusation isnt the best and the wrongest approach to go about it.

Thanks
I read your old post it seems your wife is SS so dont come here to lie

1 Like

Re: Help! His Genotype Is AA And His Wife's Genotype Is AS But Their Daughter is SS by Layloww: 11:52am On May 12, 2015
If I may ask, what kind of paternity test did they do? Was it DNA? If their answer is NO, let them try DNA.

1 Like

Re: Help! His Genotype Is AA And His Wife's Genotype Is AS But Their Daughter is SS by bigiyaro(m): 11:52am On May 12, 2015
op its either u r tellin lies or d wife played an away match, simple!
Re: Help! His Genotype Is AA And His Wife's Genotype Is AS But Their Daughter is SS by abdulkayus(m): 11:53am On May 12, 2015
bettercreature:
You got it! the fact still remain the lady was compromised during the courtship and pregnancy loading process,women are just unpredictable,she is a gonner if na me sha

Can u read at all? Did u read what the OP wrote or u just jump to comment? Or is it that u can't comprehend what was written down? No wonder them say if u want to hide something from a black man, put it in written. SMH for u guys

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Re: Help! His Genotype Is AA And His Wife's Genotype Is AS But Their Daughter is SS by Sunny4Gold: 11:53am On May 12, 2015
At times you don't believe the doctors in Nigeria because they did that to me about 8 years ago. Also no DNA facility in Nigeria.
I carried out DNA testing through DDC/DNA Diagnostics center in December 2013 only to find out I am NOT the father of the baby.

My sample and that of the baby in question was collected by one of the doctors and sent the sample through DHL to the DNA center in USA, we got the result like 12 days later. I later confronted the doctor that you told me I was the father of the baby 8 years ago, he denied

1 Like

Re: Help! His Genotype Is AA And His Wife's Genotype Is AS But Their Daughter is SS by Reggyflow4u(m): 11:53am On May 12, 2015
tpiadotcom:


then he should accept the results and stop broadcasting everywhere.

is he trying to avoid caring for the child because of the SS status?
Re: Help! His Genotype Is AA And His Wife's Genotype Is AS But Their Daughter is SS by sammhi(m): 11:53am On May 12, 2015
they shld go nd redo their genptype again if still same then let the man do a DNA test on the child
Re: Help! His Genotype Is AA And His Wife's Genotype Is AS But Their Daughter is SS by ojeffo: 11:53am On May 12, 2015
HAVE HE GONE TO THE HOSPITAL WHERE THE CHILD WAS BIRTHED??....WE SHOULDNT FORGET WE LIVE IN A WICKED UNSAFE WORLD WHERE NURSES AND MIDWIVES SWITCH BABIES AT BIRTH

3 Likes

Re: Help! His Genotype Is AA And His Wife's Genotype Is AS But Their Daughter is SS by darenawti(m): 11:54am On May 12, 2015
Mutation.....that's the reason.....gene abnormality

1 Like

Re: Help! His Genotype Is AA And His Wife's Genotype Is AS But Their Daughter is SS by Horlufemi(m): 11:54am On May 12, 2015
sorry to say. check the husbands brother. he is the culprit. if the brother is AS. ERM ERM check the brother.

They should do all the test abroad.

paternity DNA. genotype etc
Re: Help! His Genotype Is AA And His Wife's Genotype Is AS But Their Daughter is SS by onatisi(m): 11:54am On May 12, 2015
The woman is lying but no matter the number of paternity test he does ,the results will always point to him as the father. Because certain spiritual forces are only allowing them to see what they the spiritual forces want them to see. Even if he goes to russia and usa ,the results will still be the same. Aye le !
Re: Help! His Genotype Is AA And His Wife's Genotype Is AS But Their Daughter is SS by femi4: 11:54am On May 12, 2015
Missonas:


Chai femi scatter grin they should jst divorce.thkGod say d op is nt the person on question o
Yes now, instead of wasting their money and bringing ss children into this world.
Re: Help! His Genotype Is AA And His Wife's Genotype Is AS But Their Daughter is SS by Nobody: 11:54am On May 12, 2015
Your friend is AS, he should re-check.
Re: Help! His Genotype Is AA And His Wife's Genotype Is AS But Their Daughter is SS by skondo09(m): 11:55am On May 12, 2015
im still wondering 'o pakaso'
Re: Help! His Genotype Is AA And His Wife's Genotype Is AS But Their Daughter is SS by Oahray: 11:55am On May 12, 2015
dorox:
There is a very rear condition called chimerism which I think the father of the girl has.
Basically, the man has two different dna and depending on the organ or part of his body that is tested, the result can be totally different.
You can google chimerism for a detailed e planation.
yeah... This is actually a possibility. Unlikely though.

He should go for a dna test if he can afford it.
Re: Help! His Genotype Is AA And His Wife's Genotype Is AS But Their Daughter is SS by baywatch84(m): 11:55am On May 12, 2015
It can only be possible if the woman in question has sexual intercourse with another man the same day as she had sex with her husband, but the man outside did it first and the husband can be a two minute brother that can't last five minute during sex, only to get the woman pregnant with mixed sperm, don't quote me wrong it is possible to have a set of twins for a different father.
Re: Help! His Genotype Is AA And His Wife's Genotype Is AS But Their Daughter is SS by Fratello(m): 11:55am On May 12, 2015
Behira:
shocked Dis is very rare
Yeah, those body are more Rare.
Re: Help! His Genotype Is AA And His Wife's Genotype Is AS But Their Daughter is SS by Reggyflow4u(m): 11:56am On May 12, 2015
[/color][color=#990000]He is only trying to seek for professional knowledge on what could lead to that. It could be an eye opener to us all.....
then he should accept the results and stop broadcasting everywhere.

is he trying to avoid caring for the child because of the SS status?[/quote]
Re: Help! His Genotype Is AA And His Wife's Genotype Is AS But Their Daughter is SS by possibilita(m): 11:56am On May 12, 2015
If everything about this story is true then I will say there is a possibility of gene dormancy here,it may be that the one husband's parent have AS and has passed it to the husband. This is a field our expert haven't check maybe they should do more research og Genotype dormancy.

1 Like

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