₦airaland Forum

Congrats to my bro..victor..chem eng graduating wif a 3.68.. I love you..All d best..

Someone carrying a faulty gene is far less susceptible to malaria(the malaria parasite multiples normally inside normal RBC). AA pple often have malaria depending on their hygiene and contact with its vector. AS can develop it but its minimal..But SS? i dont think so..cos plasmodium can survive in that sickle blood and needs oxygen to multiply..Fank u

Symptoms..

The major xtics are anaemia. The sickle cells are useless and have to be broken down. They tend to jam in capillaries and small blood vessels and prevent normal blood flow. The kidney and joints are also affected. The blocking of blood vessels causes pain in the arms, leg, back and stomach which can be very severe.

Children with SCD are usually feel quite well for most of the time and can live relatively normal lives. However, they will generally suffer occasional 'sickle cell crises' when a sudden worsening of pain, infection or anaemia may occur..

Cause..

In 1949, a team of workers led by Linus Pauling showed that haemoglobin from SCD sufferers(HbS), is different from that of normal adult haemoglobin(HbA). Through electrophoresis, it was revealed that at pH 6.9 the overall charge on HbS is +ve whereas it is -ve in HbA.

In 1956, Ingram showed that this difference was due to a single amino acid.
Haemoglobin is made of four polypeptide chains. two alpha and two beta chains. The fault occurs at the sixth amino acid in the second beta chain..where valine(a non polar and hydrophobic(water hating) amino acid) repalces glutamic acid(a polar and hydrophilic(water loving)amino acid).

The presence of valine makes deoxygenated HbS less soluble. So when HbS loses oxygen the molecules come out of solution and crystallize into rigid rod-like fibres.

Now your question...

In 1904, the disease was discovered by a young Chicago doctor named Jamed Herrick who examined a 20 year old black college student who had been admitted to hospital complaining of a variety of symptoms. These included fever, headache, weakness, dizziness and cough. What was striking was the appearance of d patient's RBC under the microscope. Herrick descibed them as sickle-shaped.

The patient's haemoglobin level was about half normal,in other words he was suffering from anaemia(lack of haemoglobin).

Symptoms...

@bluetooth. For your question, the issue is that whoever has SCD has the name implies 'sickle cell', the sufferers blood cell takes a sickle shape there by depriving the blood of oxygen.

The fact is carriers (AS) can develop malaria,(AA) develop it very well cos their blood is okay for d malaria parasite..but(SS)..no..u can prove me wrong cos i dont know much..i'll bring my proof later..cheers

@kemiola, that na yoruba proverb..u try sha..

sumtin like 'sumtin dey wey chicken dey chop before corn come'.

Mumu beaf say we are harmed and ready..

Meaning...

If we lose(i and my boss-gej).. There's going to be a war..

Before?? av always known dat war is going to be inevitable..d wat naija is goin..there's goin to be a bad revolution..watch out!!!

This revolution is what will clean up Nigeria..

I knew dis guy when we started 100 leve back in c.u back then..now he's an inspiration..now 4.99 is very possible..it depends on d unit of d course he had a B.

My dear, Pharmacy is d best course in dis world..u'd enjoy it..What skul were u admitted to?

bch microbiology,public admin,geology,med lab science,nursing,english..should not be on dat list..

personally i dont believe there is any tough course..so dont go telling ur younger once not to read any course(wat if d person is destined to be a doctor or pharmacist?)..am a pharmacy student..it not easy gaining admission..but its worth trying..

@ u all should ask abayomin for anything..he's approachable and very nice..he'll give u all d info u need..he helped us a lot during our time(himself and solconcept)..

for d science stds, dont be scared d exam is so so simple...just read ur jamb pq and solve d questions there and master them..d exam is not tough..but u need to read(u must score above 20 to be considered for admission)..

Goodluck...

And still selling fast..Fanks josh..

@lisa, wats amazing, adultery??

@ayo..i wasnt banned..i just decided to operate from another profile..

@deecash, u said u love intimacy, then u need to get married asap..my opinion.

@tpia, are u high on soft piss run away before i send u e-slap..

@deedee, well i dont know much..but i suggest u give him a little space but given the distance, it depends on how often u guys talk..but u didnt answer d question asking ur reaction if he doesnt call u for a long time..

wat i know is an equation..ur spouse equals ur best friend..and bout his wife..i doubt she's okay with it..i rili doubt..she might not show it..women are that complex..but deep somewhere she is watchin ur proximity to her husband..im sure of dat..

hey ayo..so na here u dey catch ur fun..omo my day has been so so dry and boring after dat closed thread...dis is me

@deecash..find out what jesus said bout marriage in matthew..i fink it will ansa ur question..

##retires to bed##

@kokoA..true talk joor...

@freecocoa..haba thats unfair..na because say no be u dey there u for sabi as e take be..baba dont worry..God will protect u..

@sexkill...na true ooo..after d success of d first one..dis one cant stand..but i blame u for dat.. y?

because if u had allowed d fighting and abusing to go on, trust me we will have five more threads with a hundred pages..

##lurking around##

well this doesnt seem like it at all..dat intro was boring..

we need stories to precipitate..and we dont need people like idowu here ooo..we need normal people...cheers

another pic.

Nafdac number is A4-5134. Attractive packaging, the tablet comes in Alu Alu Blister Pack.

A pharmacist is also needed at sango area of ogun state urgently. Interested applicants should send a text to 08187162480, or send a mail to jutapharmngltd@yahoo.com.

joshuapharm:
does it have nafdac number and what are you doing about fakers. expiry dates nd stuffs. we're expecting it and goodluck.

Yes it does and i'll communicate that soon. About the fakers, we have a sales team brooding over this, we've decided not to distribute to idumota yet, we've been given a couple of good advices from notable marketers. We'll surely find a way i know. Ideas and advices from you and other good Nigerians will be given utmost consideration. We're here to serve.

Its only 200 naira.

Jutaflox? Yes, Jutaflox(ofloxacin 200mg) tablet from Juta Pharmacy Limited is already in the market and would touch down at your neighbourhood pharmacy very soon. For more enquiries, pls send a text to 08187162480 or send us a mail @ jutapharmngltd@yahoo.com.

Experienced and qualified pharmacist should send his or her cv to jutapharmngltd@yahoo.com or send a text to 08187162480. Our Pharmacy located at council bus stop, ikotun road needs a supt pharmacist and that at ayobo need a locum pharmacist . Marketing skills and experience is an advantage. The job comes with good pay and satisfactory bonuses.

Experienced and qualified pharmacist should send his or her cv to jutapharmngltd@yahoo.com or send a text to 08187162480. Our Pharmacy located at council bus stop, ikotun road needs a supt pharmacist and that at ayobo need a locum pharmacist . Marketing skills and experience is an advantage. The job comes with good pay and satisfactory bonuses.

bros av gotten my accomodation nd there cant be lectures without a time table. anyways pls i need someone to teach me physics and maths. tutorials or something. pls anyone?

plsssss abeg notify us if dey start collecting school fees and when lecture time table comes out and when lectures will start. pls i need someone that takes maths and physics tutorial urgently. you guyz dat r in school pls fill us in on what is happening.

Please when is it likely that we start lectures, what is the procedure of registration for those who have done their verification to school fees level(third verification).

@ abayomi, no vex, wat happened was dat i couldn't locate ur shop. I think u should re-explain 2 nairalanders. It's lyk its near cesap building.

Guyz d verification process is not tough. Give d photocopy nd d original of d requirement 2 d officer. But make sure ur tax clearance receipt is well stamped front nd back. Abayomi thanks a lot cos u saved me a lot of stress.