ikevin:
Now, I am sick and tired of this nonsense argument about career courses and which is better. I am appealing to medical students on this forum to stop arguing with those who always argue about the importance of their course to medicine. We've derailed way too much. Other fields are appreciated on this forum as long as you are updating people's knowledge, you guys might as well create your own forum (just saying). No one discusses questions again, no one brings medical situations and opinions any longer. All you guys do is to argue how dentists collect higher salary than doctors. I strongly feel my fellow medical students are above this depraved reasoning and arguments. Let us make this forum academic, informative and truly medical. Thank you.

annoying really
Had to leave the thread for a while hoping that when I return it would have subsided
It's just disappointing

RoastedCorn:
you are actually the 1 that should be optimistic . . . .the statistics favours dentistry than medicine

yea yea.. We agree

Guys,pls am an aspiring mbbs student applied 4 oau,is it d regular 6 yrs dat is spent in d medical school plus 1 year 4 internship?.Nw it's 7yrs plus 1yr(internship) which makes 8yrs,i jus want an oau medical student 2 pls explain d situation 4 oau medical student nd i will really appreciate it.Cuz i hear sum spend up 2 10yrs.

Roastedcorn, I think it's high time you sheath your sword forever...This thread has been grossly derailed., and it's not healthy, remember many aspirants visit this thread on daily basis, some are depressed and really need to be motivated.
I believe it will be for the good of all, if we channel our energy towards more productive arguments.
whether medicine or dentistry, let's work hard, be the very best we can be and build an enviable health care system...just like the Indians.
Please we're adults, it's okay.

charleymed:
Roastedcorn, I think it's high time you sheath your sword forever...This thread has been grossly derailed., and it's not healthy, remember many aspirants visit this thread on daily basis, some are depressed and really need to be motivated.
I believe it will be for the good of all, if we channel our energy towards more productive arguments.
whether medicine or dentistry, let's work hard, be the very best we can be and build an enviable health care system...just like the Indians.
Please we're adults, it's okay.

much respect sir,
that's why i tried resisting any arguement but zellie kept pushing

happy sunday docs!

RoastedCorn:
much respect sir,
that's why i tried resisting any arguement but zellie kept pushing

good to hear u tried resisting , but even if zellie keep pushing, u shouldn't mind ( its a sign that ure greater than him in understanding, replying an uninformed being makes u look like him somehow)
Rep MEDIPORT, sir Charleymed( keep up the good work)

Drguzzykola:

good to hear u tried resisting , but even if zellie keep pushing, u shouldn't mind ( its a sign that ure greater than him in understanding, replying an uninformed being makes u look like him somehow)
Rep MEDIPORT, sir Charleymed( keep up the good work)

okay, noticed sir!,zelllie is a girl . . . One love.

I would like to hear your opinion on this. A man is undergoing CNS ischaemic response (increased peripheral resistance, but bradycardia to increase arterial blood pressure). What is the essence of bradycardia in elevating blood pressure? What law is being obeyed? Just your thoughts.

ikevin:
I would like to hear your opinion on this. A man is undergoing CNS ischaemic response (increased peripheral resistance, but bradycardia to increase arterial blood pressure). What is the essence of bradycardia in elevating blood pressure? What law is being obeyed? Just your thoughts.

Bradycardia increases sympathetic discharge to heart (thereby increasing chronotropic and dromotrotic effects) by reducing nervous outflow from the carotid and aortic bodies to the vasomotor and cardiorespiratory centres in the brain stem. This means that, the lower the blood pressure (bradycardia) the lesser the excitation of the carotid and aortic bodies, and the more the excitation of the CNS areas mentioned, which then increases sympathetic discharge to the heart and blood vessels, and finally elevating blood pressure.
I'm not sure about the law, but it's a negative feedback reflex.

ikevin:
I would like to hear your opinion on this. A man is undergoing CNS ischaemic response (increased peripheral resistance, but bradycardia to increase arterial blood pressure). What is the essence of bradycardia in elevating blood pressure? What law is being obeyed? Just your thoughts.

But if your asking for the reason why bradycardia was associated with the man's increased blood pressure, then it's the other way round. just like a compensatory effect. increased blood pressure increases nervous outflow to the CNS, which in turn reduces sympathetic discharge to the heart and blood vessels.

Finally something productive @ikevin and @charlymed, so of me don't understand what that means tho, looks like greek. Thumbs-up tho

During CNS ischaemic response, there is reduced blood flow to the vasomotor centres which is bad. This centre therefore induce the response, i.e. Increased peripheral resistance (sympathetic effect on blood vessels) but reduces the heart rate (bradycardia). Bradycardia obeys the Frank-Sterling law of the heart under physiological range by increasing end-diastolic volume, therefore increasing stroke volume, when this is considered with increased peripheral resistance, arterial blood pressure rises greatly. I appreciate the responses so far.

How come am just seeing this??

Jolllyjoy:
How come am just seeing this??

because you are a romancelander

FINgames:
because you are a romancelander

mayb

ikevin:
During CNS ischaemic response, there is reduced blood flow to the vasomotor centres which is bad. This centre therefore induce the response, i.e. Increased peripheral resistance (sympathetic effect on blood vessels) but reduces the heart rate (bradycardia). Bradycardia obeys the Frank-Sterling law of the heart under physiological range by increasing end-diastolic volume, therefore increasing stroke volume, when this is considered with increased peripheral resistance, arterial blood pressure rises greatly. I appreciate the responses so far.

I get you now. I guess I didn't understand your question at first. Thanks.
But I will appreciate if you can through more light on why blood supply to the vasomotor centre only, is affected. or is it that a particular artery is occluded or thrombosed? ?
And secondly, I don't understand how bradycardia (decreased heart rate) increases stroke volume.
Finally, the sympathetic discharged from the vasomotor centres to the blood vessels (increased TPR) is quite understandable, but the ensuing bradycardia without the involvement of hering-bruer reflex is not that clear to me.
so, please clarify.

Millex:
Finally something productive @ikevin and @charlymed, looks like greek. Thumbs-up tho

pls anyone with info on unical direct entry medicine. do they write post DE and is the admission based on merit ?

Jolllyjoy:
How come am just seeing this??

the forum used to be very informative dear....

charleymed:
I get you now. I guess I didn't understand your question at first. Thanks.
But I will appreciate if you can through more light on why blood supply to the vasomotor centre only, is affected. or is it that a particular artery is occluded or thrombosed? ?
And secondly, I don't understand how bradycardia (decreased heart rate) increases stroke volume.
Finally, the sympathetic discharged from the vasomotor centres to the blood vessels (increased TPR) is quite understandable, but the ensuing bradycardia without the involvement of hering-bruer reflex is not that clear to me.
so, please clarify.

reduced blood supply to the VMC due to hypotension induces the response explained in order to increased blood supply to the neurons of the VMC,
With bradycardia, more blood fills the atria, therefore more blood fills the ventricles therefore increasing stroke volume (this increases cardiac output which is stroke vol * heart rate, but the vol is more imp), note that blood pressure is dependent on cardiac output and peripheral resistance.

ikevin:
reduced blood supply to the VMC due to hypotension induces the response explained in order to increased blood supply to the neurons of the VMC,
With bradycardia, more blood fills the atria, therefore more blood fills the ventricles therefore increasing stroke volume (this increases cardiac output which is stroke vol * heart rate, but the vol is more imp), note that blood pressure is dependent on cardiac output and peripheral resistance.

Ok. Thanks. I guess the bradycardia in this case is not as a result of the CNS ischaemic response directly, I think I understand what you meant now. It's actually stroke volume that's dependent on Frank-Sterling law of heart not cardiac output as I thought initially, so I'm clarified on that now. But I still have a problem with your answers...bradycardia in most will not increase cardiac output, since cardiac output is largely dependent on the heart rate, which is not elevated in bradycardia. Though elevation of blood pressure as a result of CNS ischaemic response is feasible, but this mainly due increased total peripheral resistance(increased sympathetic discharge to the blood vessels), because bradycardia in most cases does not increase cardiac output, and blood pressure is a product of cardiac output and TPR.

ADBSunkanmi:
Guys,pls am an aspiring mbbs student applied 4 oau,is it d regular 6 yrs dat is spent in d medical school plus 1 year 4 internship?.Nw it's 7yrs plus 1yr(internship) which makes 8yrs,i jus want an oau medical student 2 pls explain d situation 4 oau medical student nd i will really appreciate it.Cuz i hear sum spend up 2 10yrs.

for now, officially, medicine is 6yrs in OAU...albeit, due to incessant strikes, you could as well put it @7yrs...


Anyone that spent 10 yrs in oau medical school must have had a repeat(which not uncommon in medical school).


All medical students in Nigeria must undergo a compulsory 1yr internship b4 being fully registered(not to worry, you would be paid)

charleymed:

Ok. Thanks. I guess the bradycardia in this case is not as a result of the CNS ischaemic response directly, I think I understand what you meant now. It's actually stroke volume that's dependent on Frank-Sterling law of heart not cardiac output as I thought initially, so I'm clarified on that now. But I still have a problem with your answers...bradycardia in most will not increase cardiac output, since cardiac output is largely dependent on the heart rate, which is not elevated in bradycardia. Though elevation of blood pressure as a result of CNS ischaemic response is feasible, but this mainly due increased total peripheral resistance(increased sympathetic discharge to the blood vessels), because bradycardia in most cases does not increase cardiac output, and blood pressure is a product of cardiac output and TPR.

the response basically wants to increase blood pressure. B.P is a product of cardiac output and TPR. So on one hand TPR is increased by sympathetics while cardiac output is increased by inducing bradycardia which might seem counter-intuitive. Now, if tachycardia is induced, it wud mean less time to fill the heart with blood, therefore by inducing bradycardia, more blood enters the heart therefore more blood is pumped out therefore increasing cardiac output. I understand that cardiac output is a product of stroke volume and heart rate, but increasing stroke volume is more important than just increasing the heart rate with less blood to pump.

ikevin:
the response basically wants to increase blood pressure. B.P is a product of cardiac output and TPR. So on one hand TPR is increased by sympathetics while cardiac output is increased by inducing bradycardia which might seem counter-intuitive. Now, if tachycardia is induced, it wud mean less time to fill the heart with blood, therefore by inducing bradycardia, more blood enters the heart therefore more blood is pumped out therefore increasing cardiac output. I understand that cardiac output is a product of stroke volume and heart rate, but increasing stroke volume is more important than just increasing the heart rate with less blood to pump.

You have a strong point bro...medicine is very dynamic.
what of am thinking of something like this.....normal; stroke volume 70ml and heart rate 75 beats/min=5250ml/min (cardiac output) and for Bradycardia; heart rate 40 beats/min and stroke volume 90ml=3600ml/min.
so do you think that the cardiac output has been increased? Lols.
That's why I'm still suggesting that in the presenting case, the TPR which increases as a result of sympathetic discharge to the blood vessels is a more appropriate parameter for assessing the increased blood pressure, not bradycardia.unless where clearly stated, that's in magnitude...both for heart rate and stroke volume.
Most of the time cardiac output tend to decrease with bradycardia depending on the magnitude. That's more reason why tachycardia (as a result of sympathetic discharge to the heart) is often associated with increased blood pressure.

angiography:

for now, officially, medicine is 6yrs in OAU...albeit, due to incessant strikes, you could as well put it @7yrs...


Anyone that spent 10 yrs in oau medical school must have had a repeat(which not uncommon in medical school).


All medical students in Nigeria must undergo a compulsory 1yr internship b4 being fully registered(not to worry, you would be paid)

Would? or will?

charleymed:
You have a strong point bro...medicine is very dynamic.
what of am thinking of something like this.....normal; stroke volume 70ml and heart rate 75 beats/min=5250ml/min (cardiac output) and for Bradycardia; heart rate 40 beats/min and stroke volume 90ml=3600ml/min.
so do you think that the cardiac output has been increased? Lols.
That's why I'm still suggesting that in the presenting case, the TPR which increases as a result of sympathetic discharge to the blood vessels is a more appropriate parameter for assessing the increased blood pressure, not bradycardia.unless where clearly stated, that's in magnitude...both for heart rate and stroke volume.
Most of the time cardiac output tend to decrease with bradycardia depending on the magnitude. That's more reason why tachycardia (as a result of sympathetic discharge to the heart) is often associated with increased blood pressure.

I enjoyed your posit, yet this response does not normally occur in healthy individuals, it is a severe response to a severe condition whereby there is reduced blood flow to the centre regulating the CVS in the medulla. It would be unfair to just assume 90ml since this response is a severe one. Although, Ganong stated that this response and the CVS response to atrial natriuretic peptide are two counter-intuitive processes in CVS. You have to appreciate that the response is counter-intuitive. Other processes in CVS regulation follow normal reasoning as you are suggesting. I strongly like your reasoning, what sch, I rep Delsu by the way.

Dbrainiac1:


Would? or will?

well, I used would....and that wasn't wrong
if you had followed the pattern of my sentences, it was pertinent I used 'would'.
you can use would in lieu of will

modal auxiliaries don't follow concord rules.
you could use one in place of the other depending whether it's American or British English. For example; "shall I help you with the homework?? is British while 'should I help you with the homework??' is American

2. Whether you're being authoritative, exacting, commanding or rather pleading, expressing possibility, requesting politely(respectively) says much on the one to use...

can you bring that box??'
could you bring that box??


would is used for habitual things- whilst expressing the future judging from the past(the reason why I used 'would');
I would be paid at month end(you've always been receiving ur payment at month end, this one no exception)
I will be paid at month end(no reference to whether you had been having ur payment b4 at month end)



3. would, could, and should could be used as past form of will, can, shall...


I don't really know why I'm typing this tho

ikevin:
. It would be unfair to just assume 90ml since this response is a severe one..

lols. you're good...it's funny how dynamic medicine is, almost everything seem to be correct.
MBBS-unijos.

Dbrainiac1:


Would? or will?

Bro, Learn to ignore somethings...Some corrections could be embarrassing. Maybe it was just a mistake.

charleymed:

lols. you're good...it's funny how dynamic medicine is, almost everything seem to be correct.
MBBS-unijos.

at times it would seem beyond understanding, very frustrating. Hello to you guys over there...

ikevin:
at times it would seem beyond understanding, very frustrating. Hello to you guys over there...

LOL
thanks bro