tpiah!:

thank you

astranger:

Nice place to start, if you can understand what is going on
http://mammary.nih.gov/reviews/lactation/McCarthy001/index.html

tpiah!:

thank you

Since there was a great deal of enthusiasm for the importance of oxytocin in regulation of behavior, an obvious next step seemed to be to knock it out. Two different groups developed oxytocin knock out mice and there was great consternation when it was reported, as seen here, that oxytocin was not required for maternal behavior in mice

astranger:


Nice place to start, if you can understand what is going on

http://mammary.nih.gov/reviews/lactation/McCarthy001/index.html

astranger:

Since there was a great deal of enthusiasm for the importance of oxytocin in regulation of behavior, an obvious next step seemed to be to knock it out. Two different groups developed oxytocin knock out mice and there was great consternation when it was reported, as seen here, that oxytocin was not required for maternal behavior in mice

However, the initial reports of oxytocin inducing maternal behavior in the rat were not without some controversy. Different labs were having difficulty replicating the findings and issues such as the purity of the oxytocin, the strain of rat used and the testing paradigm were all considered. Susan Fahrbach again made a major contribution to the field when she noted that some investigators tested their subjects in their home cage whereas others moved the subject to a testing arena some time before the beginning of the behavioral test. Rats are adverse to novel environments and the movement to a testing arena would be predicted to induce a stress response. Susan directly tested the influence of the testing conditions by treating females with oxytocin and testing in their home cage or a novel environment. As you can see here, the oxytocin was only effective when the animals were tested in a novel environment, suggesting there was an interaction between the stress response and the action of oxytocin on maternal behavior.

Finally, as I have tried to demonstrate, generalizing even from rats to mice is fraught with difficulties. Trying to further draw conclusions regarding the hormonal basis of maternal behavior in humans may seem completely out of reach. However, given the frequent news reports of women failing to care for their newborn infants, i.e. a lack of the onset of maternal behavior, this is not a health problem of trivial significance. Certainly there are cultural and social influences involved in these tragic instances of infanticide, but there are also likely to be biological ones as well

chaircover:

Let me come in here by saying that I know of at least one hormone that is produced in pregnancy that can cause bad moods in pregnant women.

HCG is produced in pregnancy and for the few unfortunate ones like me who have very high levels secreted during pregancy, it can cause hyperemesis gravidarum, which results in several hospital admissions during the pregnancy due to dehydration.

You cannot be throwing up 7 times a day and cannot even smell common smells like coffee or deodorant spray with out throwing up and expect to be happy go lucky.

astranger:

This is the conclusion by the researchers, and mind you Tpiah, it is an NIH sponsored research, not some beer parlour talk like your "yahoo ask" and the other link you posted, what is it again?

tpiah!:

the spitting nko? [for those who have it].


not calming or happiness-inducing in any way.

tpiah!:

the article doesnt contradict anything i said.

Since there was a great deal of enthusiasm for the importance of oxytocin in regulation of behavior, an obvious next step seemed to be to knock it out. Two different groups developed oxytocin knock out mice and there was great consternation when it was reported, as seen here, that oxytocin was not required for maternal behavior in mice.

tpiah!:

pregnancy hormones.

tpiah!:

^^look, you cant beat me at this game.
i said hormone[b]s[/b]; you only referenced oxytocin.
besides, check post #35.

Hormones don’t CAUSE external behavior, they alter the activity in various brain areas to change the way the brain responds to various stimuli, they also change sensitivity in the genital areas.
http://www.theglaringfacts.com/sex-and-hormones/

tpiah!:

^^are you really in the medical field?

i actually didnt believe you were.

tpiah!:

by medical i mean health field and related professions.

chaircover:

Let me come in here by saying that I know of at least one hormone that is produced in pregnancy that can cause bad moods in pregnant women.

HCG is produced in pregnancy and for the few unfortunate ones like me who have very high levels secreted during pregancy, it can cause hyperemesis gravidarum, which results in several hospital admissions during the pregnancy due to dehydration.

You cannot be throwing up 7 times a day and cannot even smell common smells like coffee or deodorant spray with out throwing up and expect to be happy go lucky.

chaircover:

@Jenny LOL How I wish it was like that. For me it was from the 6th week to when I went into labour. With my daughter I was even throwing up a day after I had her & was fighting the doctors for not giving me something to stop the sickness.
During the pregnancy, I used to look at the calendar and think to my self will I ever reach these 40 weeks? I had permanent sore throat and pain in my chest from throwing up all the time.
[b]My only consolation then was that I read somewhere that women with high levels of HCG had a very low incidence of miscarriage.[/b]People that dont want Mr CC's trouble have learnt not to ask him about us having another baby, cos bless him, he suffered nearly as much as I did

tpiah!:

they said pregnancy related sickness is worse with girls than boys, though i'm not sure how true this is.

ie when the baby is a girl.

chaircover:

@DR fstranger LOL

I didn't have an epidural for my daughter. I didn't get to the hospital in time for all that. All I had was gas and air in the ambulance. That nasty metallic taste in my mouth didn't depart until the 2nd day after delivery.

@Tpiah I dont think its any different

tpiah!:

oh, alright.

that's what i heard, but people say all kinds of things anyway.