mjlumideee: y is Africa alwaya a test ground for these ailment, most especially malaria?

Damojo: Time to invest in GSK shares!

tallceejay:

I thot they said non-profit. Besides a twist to all this means, a lot of people will be put out of business....producers of insecticide, local mosquito coil, mosquito nets, etc

brosun: From test trial, the world’s first vaccine to tackle malaria, a disease that threatens the life of about 3.3 billion worldwide, will soon be available in commercial quantity for the treatment of the disease.

British drug maker, GlaxoSmithKline (GSK), is seeking regulatory approval to produce the malaria vaccine for sale, after trial data showed that it had cut the number of cases in African children.

Experts Tuesday welcomed the bid, saying they are optimistic about the possibility of the world's first vaccine being deployed to tame malaria, after the trial results.

According to the World Health Organisation (WHO), malaria, a mosquito-borne parasitic disease, kills hundreds of thousands of people worldwide yearly, with an estimated 219 million cases of the disease reported in 2010, causing an estimated 660,000 deaths.

But scientists said an effective vaccine was crucial to attempts to eradicate the disease instead of the drug regimen being used now to fight it.

The vaccine known as RTS,S was found to have almost halved the number of malaria cases in young children in the trial and to have reduced by about 25 per cent the number of malaria cases in infants.

GSK is developing RTS,S with the non-profit Path Malaria Vaccine Initiative (MVI), supported by funding from the Bill & Melinda Gates Foundation.

Researchers found out that the vaccine, which is being developed in the US, protected 12 out of 15 patients from the disease, when given in high doses.
The method is unusual because it involves injecting live but weakened malaria-causing parasites directly into patients to trigger immunity.

"Many millions of malaria cases fill the wards of our hospitals," said Halidou Tinto, a lead investigator on the RTS,S trial from Burkina Faso.

"Progress is being made with bed nets and other measures, but we need more tools to battle this terrible disease,” Tinto added.

The malaria trial was Africa's largest-ever clinical exercise involving almost 15,500 children in seven countries.

The findings were presented at a medical meeting in Durban, South Africa.http://www.thisdaylive.com/articles/experts-welcome-world-s-first-malaria-vaccine/161115/

lilslick: pls wat is malaria?

texazzpete:

1. Clinical testing was done in the US
2. Africa has the biggest concentration of malaria in the world.

I wish you clowns would stop making light of this issue. Nearly a million children die of malaria every year. You people should be jumping with joy instead of all this bullcrap FUD.

If you're asking why Africans have lots of malaria cases, why not go and ask whatever deity you believe in?

escobar07:

There is nothing usual about that. it's not a novel idea.

Damojo: Time to invest in GSK shares!

noblefada:
No the clinical trials were done in Africa. I won't be celebrating just yet, I followed the trials and know a little about malaria, results of trials were not so convincing and the protection is just for about a year. Will keep my fingers cross until 2 yrs after mass deployment.

Tinkybabe:

Thank you!that caught my attention too.

Good development though I'm yet to fathom why it took them that long to develop a vaccine if the development is limited to just injecting people with attenuated malaria parasites.

I'm still uncertain about the efficacy of this vaccine,but fingers crossed.

That said,kudos to GSK on the attempt.

vowiski:

What is the meaning of a Vaccine? Nothing we won't read on NL..

texazzpete:

if it was able to protect a large proportion of children injected with the vaccine, why is this not cause for celebration?

Kenny4lyfe: Bad news for Antimalarial Combination Therapy (ACT) manufacturing companies!

fellow nairalanders, if you don't chart a way forward for our continued existence as a country, who will?

Join the conversation right here -»» https://www.nairaland.com/1469605/national-dialogue-conference-nairaland-committee

noblefada:
Read the original scientific report, then you'll have an idea of it's actual efficacy. Secondly, one of the malaria parasite is the most stubborn organism ever known to man and has so far defied everything thrown @ it.

manjiggy:
I've worked with malaria parasites before. I can say it is not an easy task to come up with a vaccine for malaria. Thank God it is finally here.

tallceejay:

I thot they said non-profit. Besides a twist to all this means, a lot of people will be put out of business....producers of insecticide, local mosquito coil, mosquito nets, etc