otokx:
There is no such department at the University of Port Harcourt.

what Uniport offers is Sociology. you can only offer crimology at Masters level under sociology.

blackgold90:
This is the reason we have inflation. Hoarding money in the name of piggy box

on the contrary, piggy box helps to stem the tide of inflation by reducing the volume of money in circulation.

sinaj:
Thats not true. They spend a lot of time offshores which makes it almost impossible to meet people, keep a relationship or marriage.

Sarah darling, you just went AWOL and stopped keeping in touch. Thats not fair.

there is this leaf my white boss introduced me to and it is called lemon basil. The leaf contains aphrodisiacal property that enhances one's performance. I can testify to its efficacy.

ibkayee:

That’s the general idea

issorite. At least the by tacit endorsement you and pocohantas has thrown to the use of pen knife it will serve as a warning to guys to act responsibly.

May i also add that women should try and embark on due diligence before sparking any chemistry with guys. That way the incidences of rape will be averted. There are many decent guys out there who abhors forcibly taken advantage of ladies. But most Nigeria ladies tend to have preferences for the sharp bad guys owing to their sugarcoated attribute.

pocohantas:


To kill the rapist
The only problem is, knives are messy!!!

The resort to moving with knife to a guy's house as a pre-emptive measure against any seeming attempt of rape is totally inappropriate.

i'll rather support the use of pepper spray.

The implication of deploring pen knife as a defence mechanism is the fact that it could, when not properly handled, use to sniff life on the opposite sex. And in such a case, the lady would be held culpable and charged to court for manslaughter.

fatymore:
It depends on you and the guy you are visiting... Not all men are scums...
Next time if you ain't sure..arrange to meet in an open place better still take a pen knife along

Did you say pen knife? Really aghast as to why you'll make such suggestive.

Saff:
This is an absolute lie. I can’t get this obsessive over anyone, I’m so sorry. Especially for something that only last max 7 mins. Shior

Did you say 7 minutes?

love your your scurly hair. Also wish to add that you look supercalifragalisticexpiadocious.

[quote author=krendo post=70057478]Women can be so passionate when they defend their convictions

History will remember you kindly madam Boma

That is the true spirit of the Okrika woman[/quote


On the contrary, she is from Buguma in kalabari kingdom. she is actually the elder sister to Mujahid Asari Dokubo.

TonyeBarcanista:
Graveyard matters? Even dead body have their interests protected in Nigeria

Funny you

Really find this thread helpful. Am desiring to do career switch to Supply chain Mgt. So anyone with an idea of an accredited center in Rivers state where one can pursue PGD should please furnish me with same.

can be reached via my mail: kellikoko@gmail.com

goaldynboy:




He is actually from Bayelsa! His Mother is Igbo. Grew up in Portharcourt. His father, Dele Cole was a former Ambassador! If you know, you know!!

Tonye Dele Cole is of kalabari extraction. His dad was a one time Ambassador to Brazil.

Tonye Cole is a confidante and ally of Rotimi Amaechi and is nursing the ambition to throw himself into the ring in contesting as Governor of Rivers state under the platform of APC.

There is absolutely nothing wrong in it. I can also relate. That's how my ex told me that should we get married I should be ready to move out of the two bedroom ensuite apartment my dad bequeathed to me. That she doesn't like where she will have contact with my mum. I could recall i told her that my priority is to get a land and build my own house. That I really do not feel comfortable renting a house in my state. Beside my Family house is in the heart of the capital in my state.

Guy any women that do not feel comfortable in your family house should take up the gauntlet by using her money to secure a new apartment.

it now leads me to the question, why do women like dreading their mother-inlaw?

As my friend would rightly opined " The boy is good, the boy is good, you must show working". Relationship in Nigeria is predicated on the concept of "quid pro quo".

More pics

My friend finally decided to do the needful. This Saturday, 19th May, 2018, my friend Mr. Princewill Tamunodein would be walking the aisle to say I do with his adorable sweet heart Miss. Chiamaka Ezugha in Port Harcourt.

Deji63:


Aviation School in Nigeria is for dick and Harry.

You're very wrong. Rather on the contrary, the cost implication of training a pilot
in Nigeria is in the neighbourhood of N20 million

You can go to the website of International Aviation Academy Kwara to ascertain this fact yourself . Website: www.IAC.com.ng

was seeing a documentary on some specie of birds on National Geo last month. what really intrigued me about the said program, was that some species of birds, before the male could freely mate with the female he has to satisfy her needs by providing her with food. I was really in awe after seeing the program.

So the same also applies to humans. But methinks that relationship should be anchored on the principles of "quid pro quo" and not the other way round. Women's own part of the relationship shouldn't just be about sex. it should go beyond that.

TheUpsetGirl1:

maybe he has been dating Nigerian ladies living in the UK...

Perhaps

allanphash7:
Osun state will dance for 8 years

hahahaha. funny you.

Tinocosta17:
Sue him and collect everything both the two cars... Useless man

in which country? Nigeria is not like US and Europe where their legal system tend to be skewed in favour of women.

MhizAJ:
She tried

Ordinary 2 bedroom flat and he fainted
If to say na duplex nko

Funny enough this same man will still fvck different girls right in that flat that his hard-working girlfriend got for him

I don't think it's wise to invest in a man or do any thing good for/to them

But is okay for a man to invest in a woman, right?

Relationship should be predicated on the principles of quid pro quo and not the other way round.

MhizAJ:
She tried

Ordinary 2 bedroom flat and he fainted
If to say na duplex nko

Funny enough this same man will still fvck different girls right in that flat that his hard-working girlfriend got for him

I don't think it's wise to invest in a man or do any thing good for/to them

But is okay for a man invest in a woman, right?

Relationship should about quid pro quo and the other way round.

DrWise:


This is a wicked lie!

Ugep has never eaten anybody and the Station has never been closed for one day.

A lot of people in NL served in Ugep, they can testify to this.

Take your lies out of here.

That Ugep people engages in cannibalism is not in doubt as it is clearly documented in the book "Tragedy of victory: on the spot Account of the Nigeria-Biafra war in the Atlantic Theatre" by Brigadier-General Godwin Alabi.

The author who fought in the Nigeria-Biafra gave a vivid account in his book on how they were fed with eba and soup containing human flesh by the Ugep people after liberating the place. That they only got to know that they ate human after they have consumed the said meat.

And guess what, the human flesh were Biafra soldiers that were killed by the Ugep people.

Scientists for the first time have successfully edited genes in human embryos to repair a common and serious disease-causing mutation, producing apparently healthy embryos, according to a study published on Wednesday.

The research marks a major milestone and, while a long way from clinical use, it raises the prospect that gene editing may one day protect babies from a variety of hereditary conditions.

But the achievement is also an example of human genetic engineering, once feared and unthinkable, and is sure to renew ethical concerns that some might try to design babies with certain traits, like greater intelligence or athleticism.

Scientists have long feared the unforeseen medical consequences of making inherited changes to human DNA. The cultural implications may be just as disturbing: Some experts have warned that unregulated genetic engineering may lead to a new form of eugenics, in which people with means pay to have children with enhanced traits even as those with disabilities are devalued.


The study, published in the journal Nature, comes just months after a national scientific committee recommended new guidelines for modifying embryos, easing blanket proscriptions but urging the technique be used only for dire medical problems.

“We’ve always said in the past gene editing shouldn’t be done, mostly because it couldn’t be done safely,” said Richard Hynes, a cancer researcher at the Massachusetts Institute of Technology who co-led the committee. “That’s still true, but now it looks like it’s going to be done safely soon,” he said, adding that the research is “a big breakthrough.”

“What our report said was, once the technical hurdles are cleared, then there will be societal issues that have to be considered and discussions that are going to have to happen. Now’s the time.”

Scientists at Oregon Health and Science University, with colleagues in California, China and South Korea, reported that they repaired dozens of embryos, fixing a mutation that causes a common heart condition that can lead to sudden death later in life.

If embryos with the repaired mutation were allowed to develop into babies, they would not only be disease-free but also would not transmit the disease to descendants.

The researchers averted two important safety problems: They produced embryos in which all cells — not just some — were mutation-free, and they avoided creating unwanted extra mutations.


“It feels a bit like a ‘one small step for (hu)mans, one giant leap for (hu)mankind’ moment,” Jennifer Doudna, a biochemist who helped discover the gene-editing method used, called CRISPR-Cas9, said in an email.


“I expect these results will be encouraging to those who hope to use human embryo editing for either research or eventual clinical purposes,” said Dr. Doudna, who was not involved in the study.

Much more research is needed before the method could be tested in clinical trials, currently impermissible under federal law. But if the technique is found to work safely with this and other mutations, it might help some couples who could not otherwise have healthy children.

Potentially, it could apply to any of more than 10,000 conditions caused by specific inherited mutations. Researchers and experts said those might include breast and ovarian cancer linked to BRCA mutations, as well as diseases like Huntington’s, Tay-Sachs, beta thalassemia, and even sickle cell anemia, cystic fibrosis or some cases of early-onset Alzheimer’s.

“You could certainly help families who have been blighted by a horrible genetic disease,” said Robin Lovell-Badge, a professor of genetics and embryology at the Francis Crick Institute in London, who was not involved in the study.

“You could quite imagine that in the future the demand would increase. Maybe it will still be small, but for those individuals it will be very important.”

The researchers also discovered something unexpected: a previously unknown way that embryos repair themselves.


In other cells in the body, the editing process is carried out by genes that copy a DNA template introduced by scientists. In these embryos, the sperm cell’s mutant gene ignored that template and instead copied the healthy DNA sequence from the egg cell.

“We were so surprised that we just couldn’t get this template that we made to be used,” said Shoukhrat Mitalipov, director of the Center for Embryonic Cell and Gene Therapy at Oregon Health and Science University and senior author of the study. “It was very new and unusual.”

The research significantly improves upon previous efforts. In three sets of experiments in China since 2015, researchers seldom managed to get the intended change into embryonic genes.

And some embryos had cells that did not get repaired — a phenomenon called mosaicism that could result in the mutation being passed on — as well as unplanned mutations that could cause other health problems.

In February, a National Academy of Sciences, Engineering and Medicine committee endorsed modifying embryos, but only to correct mutations that cause “a serious disease or condition” and when no “reasonable alternatives” exist.


Shoukhrat Mitalipov, director of the Center for Embryonic Cell and Gene Therapy at Oregon Health and Science University, is one of the authors of the new study.
LEAH NASH FOR THE NEW YORK TIMES
Sheldon Krimsky, a bioethicist at Tufts University, said the main uncertainty about the new technique was whether “reasonable alternatives” to gene editing already exist.

As the authors themselves noted, many couples use pre-implantation genetic diagnosis to screen embryos at fertility clinics, allowing only healthy ones to be implanted. For these parents, gene editing could help by repairing mutant embryos so that more disease-free embryos would be available for implantation.

Hank Greely, director of the Center for Law and the Biosciences at Stanford, said creating fewer defective embryos also would reduce the number discarded by fertility clinics, which some people oppose.

The larger issue is so-called germline engineering, which refers to changes made to embryo that are inheritable.

“If you’re in one camp, it’s a horror to be avoided, and if you’re in the other camp, it’s desirable,” Dr. Greely said. “That’s going to continue to be the fight, whether it’s a feature or a bug.”

For now, the fight is theoretical. Congress has barred the Food and Drug Administration from considering clinical trials involving germline engineering. And the National Institutes of Health is prohibited from funding gene-editing research in human embryos. (The new study was funded by Oregon Health and Science University, the Institute for Basic Science in South Korea, and several foundations.)

The authors say they hope that once the method is optimized and studied with other mutations, officials in the United States or another country will allow regulated clinical trials.

“I think it could be widely used, if it’s proven safe,” said Dr. Paula Amato, a co-author of the study and reproductive endocrinologist at O.H.S.U. Besides creating more healthy embryos for in vitro fertilization, she said, it could be used when screening embryos is not an option or to reduce arduous IVF cycles for women.

Dr. Mitalipov has pushed the scientific envelope before, generating ethical controversy with a so-called three-parent baby procedure that would place the nucleus of the egg of a woman with defective cellular mitochondria into the egg from a healthy woman. The F.D.A. has not approved trials of the method, but Britain may begin one soon.

The new study involves hypertrophic cardiomyopathy, a disease affecting about one in 500 people, which can cause sudden heart failure, often in young athletes.

It is caused by a mutation in a gene called MYBPC3. If one parent has a mutated copy, there is a 50 percent chance of passing the disease to children.


Using sperm from a man with hypertrophic cardiomyopathy and eggs from 12 healthy women, the researchers created fertilized eggs. Injecting CRISPR-Cas9, which works as a genetic scissors, they snipped out the mutated DNA sequence on the male MYBPC3 gene.

They injected a synthetic healthy DNA sequence into the fertilized egg, expecting that the male genome would copy that sequence into the cut portion. That is how this gene-editing process works in other cells in the body, and in mouse embryos, Dr. Mitalipov said.

Instead, the male gene copied the healthy sequence from the female gene. The authors don’t know why it happened.

Maybe human sex cells or gametes evolved to repair themselves because they are the only cells that transmit genes to offspring and “need special protection,” said Juan Carlos Izpisua Belmonte, a co-author and geneticist at the Salk Institute.

Out of 54 embryos, 36 emerged mutation-free, a significant improvement over natural circumstances in which about half would not have the mutation. Another 13 embryos also emerged without the mutation, but not in every cell.

The researchers tried to eliminate the problem by acting at an earlier stage, injecting the egg with the sperm and CRISPR-Cas9 simultaneously, instead of waiting to inject CRISPR-Cas9 into the already fertilized egg.

That resulted in 42 of 58 embryos, 72 percent, with two mutation-free copies of the gene in every cell. They also found no unwanted mutations in the embryos, which were destroyed after about three days.

The method was not perfect. The remaining 16 embryos had unwanted additions or deletions of DNA. Dr. Mitalipov said he believed fine-tuning the process would make at least 90 percent of embryos mutation-free.

And for disease-causing mutations on maternal genes, the same process should occur, with the father’s healthy genetic sequence being copied, he said.

But the technique will not work if both parents have two defective copies. Then, scientists would have to determine how to coax one gene to copy a synthetic DNA sequence, Dr. Mitalipov said.

Otherwise, he said, it should work with many diseases, “a variety of different heritable mutations.”

R. Alta Charo, a bioethicist at University of Wisconsin at Madison, who led the committee with Dr. Hynes, said the new discovery could also yield more information about causes of infertility and miscarriages.

She doubts a flood of couples will have “edited children.”

“Nobody’s going to do this for trivial reasons,” Dr. Charo said. “Sex is cheaper and it’s more fun than IVF, so unless you’ve got a real need, you’re not going to use it.”

https://mobile.nytimes.com/2017/08/02/science/gene-editing-human-embryos.html?referer=https://www.google.com.ng/

This drama reminds me of the post I made some months ago on nairaland on the subject matter " Most first born in Nigerian home are bastards" written by by DNA expert in Nigeria. For those desirous of reading it, here is the link:

https://www.nairaland.com/2994467/most-first-borns-nigeria-bastards

mrvitalis:
Please stop telling lies that's not Port Harcourt zoo please... As we don't presently have a zoo in ph

Doubt if you reside in Port Harcourt. Because if you do, you won't come to this platform and make such uninformed statement.

kcnwaigbo:

Last I checked Wike was not the one who forged a common Waec certificate. He has an LLB (hons)

Wike first degree was in Political science from the University of Port Harcourt before he subsequently bagged a Law degree from UST.

AjiereTuwo:

Why would someone want to leave a blessed state like Rivers, who go liv london go Somalia

Who go leave a land "flowing in milk and honey" to a famine ravaged land all in name of exposure.